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代谢综合征患者乳腺密度的测定:一项横断面研究。

Determining Breast Density in Patients with Metabolic Syndrome: A Cross Sectional Study.

作者信息

Sarvetamin Hamta Taheri

机构信息

Faculty of Medicine, Kerman University of Medical Sciences, Kerman, Iran.

出版信息

J Pharm Bioallied Sci. 2025 May;17(Suppl 1):S302-S304. doi: 10.4103/jpbs.jpbs_1954_24. Epub 2025 Apr 29.

Abstract

INTRODUCTION AND OBJECTIVE

Breast density is considered a primary factor of mammography sensitivity, which serves as an optimal tool for breast cancer screening, given the potential role of metabolic syndrome in increasing breast density. Therefore, this study aimed to determine breast density in patients with this syndrome.

METHODS AND METHODOLOGY

This cross-sectional study was conducted on 196 premenopausal women divided into metabolic syndrome and healthy groups. Mammograms were performed, and breast density was measured based on the ACR standard definition. The collected data were analyzed using the Chi-square test and SPSS software version 18.

FINDINGS

In the control group, 24% were classified as A, 28% as B, 24% as C, and 24% as D. In the experimental group, 20.8% were classified as A, 8.3% as B, 41.7% as C, and 29.2% as D ( value = 0.001). There was no significant difference between the frequency of lesions requiring further evaluation and benign lesions ( value > 0.05).

CONCLUSION

Based on the results, metabolic syndrome may increase mammographic density.

摘要

引言与目的

鉴于代谢综合征在增加乳腺密度方面的潜在作用,乳腺密度被认为是乳腺钼靶检查敏感性的主要因素,而乳腺钼靶检查是乳腺癌筛查的最佳工具。因此,本研究旨在确定患有该综合征患者的乳腺密度。

方法与方法论

本横断面研究对196名绝经前女性进行,分为代谢综合征组和健康组。进行了乳腺钼靶检查,并根据美国放射学会(ACR)标准定义测量乳腺密度。使用卡方检验和SPSS 18版软件对收集的数据进行分析。

研究结果

在对照组中,24%被归类为A类,28%为B类,24%为C类,24%为D类。在实验组中,20.8%被归类为A类,8.3%为B类,41.7%为C类,29.2%为D类(值 = 0.001)。需要进一步评估的病变频率与良性病变之间无显著差异(值 > 0.05)。

结论

基于结果,代谢综合征可能会增加乳腺钼靶密度。

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本文引用的文献

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Associations between mammographic density and serum and dietary cholesterol.乳腺密度与血清胆固醇和膳食胆固醇的相关性。
Breast Cancer Res Treat. 2011 Jan;125(1):181-9. doi: 10.1007/s10549-010-0927-7. Epub 2010 May 13.
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Sonographic evaluation of focal asymmetric density of the breast.
Ultrasound Q. 2002 Jun;18(2):115-21. doi: 10.1097/00013644-200206000-00004.
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