Sarvetamin Hamta Taheri
Faculty of Medicine, Kerman University of Medical Sciences, Kerman, Iran.
J Pharm Bioallied Sci. 2025 May;17(Suppl 1):S302-S304. doi: 10.4103/jpbs.jpbs_1954_24. Epub 2025 Apr 29.
Breast density is considered a primary factor of mammography sensitivity, which serves as an optimal tool for breast cancer screening, given the potential role of metabolic syndrome in increasing breast density. Therefore, this study aimed to determine breast density in patients with this syndrome.
This cross-sectional study was conducted on 196 premenopausal women divided into metabolic syndrome and healthy groups. Mammograms were performed, and breast density was measured based on the ACR standard definition. The collected data were analyzed using the Chi-square test and SPSS software version 18.
In the control group, 24% were classified as A, 28% as B, 24% as C, and 24% as D. In the experimental group, 20.8% were classified as A, 8.3% as B, 41.7% as C, and 29.2% as D ( value = 0.001). There was no significant difference between the frequency of lesions requiring further evaluation and benign lesions ( value > 0.05).
Based on the results, metabolic syndrome may increase mammographic density.
鉴于代谢综合征在增加乳腺密度方面的潜在作用,乳腺密度被认为是乳腺钼靶检查敏感性的主要因素,而乳腺钼靶检查是乳腺癌筛查的最佳工具。因此,本研究旨在确定患有该综合征患者的乳腺密度。
本横断面研究对196名绝经前女性进行,分为代谢综合征组和健康组。进行了乳腺钼靶检查,并根据美国放射学会(ACR)标准定义测量乳腺密度。使用卡方检验和SPSS 18版软件对收集的数据进行分析。
在对照组中,24%被归类为A类,28%为B类,24%为C类,24%为D类。在实验组中,20.8%被归类为A类,8.3%为B类,41.7%为C类,29.2%为D类(值 = 0.001)。需要进一步评估的病变频率与良性病变之间无显著差异(值 > 0.05)。
基于结果,代谢综合征可能会增加乳腺钼靶密度。