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术后疼痛管理:评估多模式镇痛的作用

Postoperative Pain Management: Evaluating the Role of Multimodal Analgesia.

作者信息

Gautam Archana, Pande Chetan, Pande Meghana

机构信息

Department of Anesthesiology, Symbiosis Medical College for Women and Symbiosis University Hospital and Research Centre, Symbiosis International (Deemed University), Lavale, Pune, Maharashtra, India.

Department of Medicine Consultant Physician and Intensivist, Life Care Hospital Pune, Maharashtra, India.

出版信息

J Pharm Bioallied Sci. 2025 May;17(Suppl 1):S314-S316. doi: 10.4103/jpbs.jpbs_1949_24. Epub 2025 Mar 6.

Abstract

BACKGROUND

Effective postoperative pain management is essential for enhancing recovery and improving patient outcomes. Multimodal analgesia (MMA) combines different analgesic approaches to optimize pain control while reducing opioid dependence. This study evaluates the effectiveness of MMA in managing postoperative pain across various surgical procedures.

OBJECTIVES

To assess the impact of multimodal analgesia on postoperative pain relief, opioid consumption, and associated side effects.

METHODS

A quasi-experimental study was conducted with 60 patients divided into a study group (n=30) receiving MMA and a control group (n=30) receiving standard pain management. Pain levels were assessed using the Visual Analog Scale (VAS) at 6, 12, and 24 hours post-surgery. Opioid consumption and the incidence of side effects were also recorded.

RESULTS

The study group reported significantly lower VAS pain scores at all time points compared to the control group. Additionally, opioid consumption was reduced, with fewer opioid-related side effects observed in the MMA group.

CONCLUSION

Multimodal analgesia effectively reduces postoperative pain, minimizes opioid use, and decreases associated side effects, supporting its broader implementation in clinical pain management strategies.

摘要

背景

有效的术后疼痛管理对于促进恢复和改善患者预后至关重要。多模式镇痛(MMA)结合了不同的镇痛方法,以优化疼痛控制,同时减少对阿片类药物的依赖。本研究评估了MMA在各种外科手术中管理术后疼痛的有效性。

目的

评估多模式镇痛对术后疼痛缓解、阿片类药物消耗及相关副作用的影响。

方法

进行了一项准实验研究,60例患者分为接受MMA的研究组(n = 30)和接受标准疼痛管理的对照组(n = 30)。术后6小时、12小时和24小时使用视觉模拟量表(VAS)评估疼痛程度。还记录了阿片类药物的消耗量和副作用的发生率。

结果

与对照组相比,研究组在所有时间点的VAS疼痛评分均显著更低。此外,MMA组的阿片类药物消耗量减少,与阿片类药物相关的副作用也更少。

结论

多模式镇痛有效减轻术后疼痛,减少阿片类药物使用,并降低相关副作用,支持其在临床疼痛管理策略中更广泛地应用。

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