前庭疾病患者的焦虑和抑郁
Anxiety and Depression in Patients With Vestibular Disorders.
作者信息
Sciscent Bao Y, Polanik Marc, Lorenz F Jeffrey, Eberly Hänel W, Whitaker Mark E
机构信息
Department of Otolaryngology-Head and Neck Surgery Penn State Milton S. Hershey Medical Center and Penn State College of Medicine Hershey Pennsylvania USA.
出版信息
OTO Open. 2025 Jun 12;9(2):e70139. doi: 10.1002/oto2.70139. eCollection 2025 Apr-Jun.
OBJECTIVE
To investigate the prevalence of depression and anxiety in patients with vestibular disorders using a large patient database.
STUDY DESIGN
Retrospective cohort.
SETTING
The TriNetX database.
METHODS
TriNetX, a deidentified database, was retrospectively queried to identify adults with vestibular disorders. The rates of anxiety and depression in patients with vestibular disorders were compared to patients without vestibular disorders within 5 years of the index event, which was set at the time of diagnosis of vestibular dysfunction.
RESULTS
On analysis of patients with and without vestibular disorders, after propensity score matching for demographics and common comorbidities, 64,153 patients were identified in each cohort. Patients with vestibular disorders were more likely to have depression (relative risk [RR] 1.37 [95% CI 1.35-1.40]) and anxiety (RR 1.51 [95% CI 1.45-1.57]) compared to the general population. Similarly, a higher rate of antidepressant use was seen in patients with vestibular disorders (RR 1.41 [95% CI 1.39-1.43]).
CONCLUSION
Patients with vestibular disorders have higher rates of depression and anxiety compared to the general population.
目的
利用大型患者数据库调查前庭疾病患者中抑郁和焦虑的患病率。
研究设计
回顾性队列研究。
研究地点
TriNetX数据库。
方法
对TriNetX（一个经过身份去识别处理的数据库）进行回顾性查询，以识别患有前庭疾病的成年人。将前庭疾病患者的焦虑和抑郁发生率与在索引事件（设定为前庭功能障碍诊断时）后5年内无前庭疾病的患者进行比较。
结果
在对有和无前庭疾病的患者进行分析时，在对人口统计学和常见合并症进行倾向得分匹配后，每个队列中识别出64153名患者。与普通人群相比，前庭疾病患者更有可能患有抑郁症（相对风险[RR]1.37[95%置信区间1.35 - 1.40]）和焦虑症（RR 1.51[95%置信区间1.45 - 1.57]）。同样，前庭疾病患者中抗抑郁药的使用比例更高（RR 1.41[95%置信区间1.39 - 1.43]）。
结论
与普通人群相比，前庭疾病患者的抑郁和焦虑发生率更高。
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