Feng Shuai, Zang Jian
Department of Otolaryngology, The First Hospital of China Medical University, Shenyang, China.
Front Aging Neurosci. 2023 Aug 1;15:1208392. doi: 10.3389/fnagi.2023.1208392. eCollection 2023.
This study aims to investigate the situation of vertigo disorder combined with anxiety and depression in patients with different types of vestibular syndrome.
A total of 330 patients with vertigo in otolaryngology outpatient department were selected, and clinical information such as age, gender, and scores of Dizziness handicap inventory (DHI), Generalized anxiety disorder-7 (GAD-7), and Patient Health Questionnaire-9 (PHQ-9) were collected. Analyzed the differences among acute vestibular syndrome (AVS), episodic vestibular syndrome (EVS) and chronic vestibular syndrome (CVS) in terms of age, gender, comorbid anxiety and depression, and the multivariate ordered logistic regression analysis was used to evaluate the relationship between the above factors and the degree of vertigo disorder.
The three types of vestibular syndrome had no significant difference in age composition, sex composition, anxiety and depression. There was no significant difference in the probability of anxiety and depression among vertigo patients of different ages and genders. The total score of vertigo disorder and each sub-item score were higher in patients with anxiety and depression. Patients with anxiety mainly manifested in EVS and CVS, while patients with depression mainly manifested in EVS and AVS. The probability of increased vertigo in anxious patients was 4.65 times that of non-anxious patients, and the probability of increased vertigo in depressed patients was 3.49 times that of non-depressed patients. Age and gender had no statistically significant effect on the degree of vertigo. In patients with EVS, anxiety and depression had a significant effect on the degree of vertigo; in patients with CVS, anxiety had a significant effect on the degree of vertigo, but depression had no significant effect.
Age and gender do not significantly affect the degree of vertigo disorder and mental state in various vestibular syndromes. Instead, anxiety and depression are the risk factors for aggravating the degree of vertigo disorder, and manifest differently in each type of vestibular syndrome. Therefore, it is necessary to use a quick scale tool to conduct a standardized screening of the psychological status of patients with vertigo.
本研究旨在调查不同类型前庭综合征患者中眩晕障碍合并焦虑和抑郁的情况。
选取耳鼻喉科门诊共330例眩晕患者,收集其年龄、性别、头晕残障量表(DHI)、广泛性焦虑障碍量表-7(GAD-7)及患者健康问卷-9(PHQ-9)评分等临床资料。分析急性前庭综合征(AVS)、发作性前庭综合征(EVS)和慢性前庭综合征(CVS)在年龄、性别、合并焦虑和抑郁方面的差异,并采用多变量有序逻辑回归分析评估上述因素与眩晕障碍程度的关系。
三种类型的前庭综合征在年龄构成、性别构成、焦虑和抑郁方面无显著差异。不同年龄和性别的眩晕患者焦虑和抑郁的发生率无显著差异。焦虑和抑郁患者的眩晕障碍总分及各分项得分更高。焦虑患者主要表现在EVS和CVS中,而抑郁患者主要表现在EVS和AVS中。焦虑患者眩晕加重的概率是非焦虑患者的4.65倍,抑郁患者眩晕加重的概率是非抑郁患者的3.49倍。年龄和性别对眩晕程度无统计学显著影响。在EVS患者中,焦虑和抑郁对眩晕程度有显著影响;在CVS患者中,焦虑对眩晕程度有显著影响,但抑郁无显著影响。
年龄和性别对各种前庭综合征的眩晕障碍程度和精神状态无显著影响。相反,焦虑和抑郁是加重眩晕障碍程度的危险因素,且在每种前庭综合征中表现不同。因此,有必要使用快速量表工具对眩晕患者的心理状态进行标准化筛查。