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[勘误] 在帕金森病的体内和体外模型中,miR-335通过靶向铁蛋白重链1促进铁死亡。

[Corrigendum] miR‑335 promotes ferroptosis by targeting ferritin heavy chain 1 in in vivo and in vitro models of Parkinson's disease.

作者信息

Li Xinrong, Si Wenwen, Li Zhan, Tian Ye, Liu Xuelei, Ye Shanyu, Huang Zifeng, Ji Yichun, Zhao Caiping, Hao Xiaoqian, Chen Dongfeng, Zhu Meiling

机构信息

Traditional Chinese Medicine Innovation Research Center, Shenzhen Hospital of Integrated Traditional Chinese and Western Medicine, Shenzhen, Guangdong 518104, P.R. China.

Guangdong Key Laboratory of Orthopedic Technology and Implant Materials, Key Laboratory of Trauma and Tissue Repair of Tropical Area of PLA, Hospital of Orthopedics, General Hospital of Southern Theater Command of PLA, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong 510010, P.R. China.

出版信息

Int J Mol Med. 2025 Aug;56(2). doi: 10.3892/ijmm.2025.5565. Epub 2025 Jun 13.

DOI:10.3892/ijmm.2025.5565
PMID:40511552
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12176272/
Abstract

Subsequently to the publication of the above paper, an interested reader drew to the authors' attention that, for the JC‑1 staining experiments shown in Fig. 5F on p. 9, the 'mimic NC' and 'inhibitor' panels appeared to show the same cells, even though the green/red ratio was different comparing between the two data panels. In addition, two further instances of duplicated data panels were identified in Figs. S2 and S3, such that data that were allegedly obtained under different experimental conditions appeared to have been derived from the same original sources. After having asked the authors to explain the errors that had occurred in assembling these figures, they responded to explain that the error in Fig. 5F resulted from the incorrect selection of source images for the channels during the image merging process, whereas the errors in Figs. S2 and S3 occurred due to mistakes made in the naming and management of image files during storage. This led to the unintentional use of incorrect images during the process of figure assembly. Moreover, the authors were able to present to the Editorial Office the original data from the JC‑1 staining experiments belonging to Fig. 5F. The Editor of has agreed that a corrigendum may be published to account for the errors made in assembling Figs. 5, S2 and S3, and the corrected versions of these figures are shown on the next page. All the authors agree with the publication of this corrigendum, and are thankful to the Editor for giving them the opportunity to present this; moreover, the Editor and the authors apologize to the readership for any inconvenience caused. [International Journal of Molecular Medicine 47: 61, 2021; DOI: 10.3892/ijmm.2021.4894].

摘要

在上述论文发表之后,一位感兴趣的读者提请作者注意,在第9页图5F所示的JC-1染色实验中,“模拟物阴性对照”和“抑制剂”组似乎显示的是相同的细胞,尽管两个数据组之间的绿色/红色比率有所不同。此外,在图S2和S3中还发现了另外两个数据组重复的情况,以至于据称在不同实验条件下获得的数据似乎来自相同的原始来源。在要求作者解释在组装这些图时出现的错误后,他们回复称图5F中的错误是由于在图像合并过程中通道源图像选择错误所致,而图S2和S3中的错误是由于存储期间图像文件命名和管理方面的失误造成的。这导致在图组装过程中无意使用了错误的图像。此外,作者能够向编辑部提供属于图5F的JC-1染色实验的原始数据。《国际分子医学杂志》的编辑同意发表一份勘误表,以说明在组装图5、S2和S3时所犯的错误,这些图的更正版本见下一页。所有作者均同意发表这份勘误表,并感谢编辑给予他们陈述此事的机会;此外,编辑和作者就所造成的任何不便向读者表示歉意。[《国际分子医学杂志》47: 61, 2021; DOI: 10.3892/ijmm.2021.4894]

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a884/12176272/c201b422c9d0/ijmm-56-02-05565-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a884/12176272/6db7d99440bc/ijmm-56-02-05565-g00.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a884/12176272/986a63fb692b/ijmm-56-02-05565-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a884/12176272/c201b422c9d0/ijmm-56-02-05565-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a884/12176272/6db7d99440bc/ijmm-56-02-05565-g00.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a884/12176272/986a63fb692b/ijmm-56-02-05565-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a884/12176272/c201b422c9d0/ijmm-56-02-05565-g02.jpg

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