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[已撤回] 华蟾毒精通过ROS/JNK/p38信号通路诱导人骨肉瘤U2OS细胞发生自噬介导的细胞死亡。

[Retracted] Cinobufagin induces autophagy‑mediated cell death in human osteosarcoma U2OS cells through the ROS/JNK/p38 signaling pathway.

作者信息

Ma Kun, Zhang Chuan, Huang Man-Yu, Li Wu-Yin, Hu Guo-Qiang

机构信息

Luoyang Orthopaedic-Traumatological Hospital and Henan Orthopaedic Hospital, Luoyang, Henan 471002, P.R. China.

College of Pharmacy, Henan University, Kaifeng, Henan 475000, P.R. China.

出版信息

Oncol Rep. 2025 Aug;54(2). doi: 10.3892/or.2025.8928. Epub 2025 Jun 20.

Abstract

Following the publication of this paper, it was drawn to the Editor's attention by a concerned reader that certain of the cellular data shown in Fig. 2C on p. 93 had already been submitted to another journal in an article written by different authors at different research institutes, which has subsequently been retracted. Moreover, upon performing an independent assessment of the data in the above paper in the Editorial Office, it emerged that flow cytometric data in Figs. 1 and 4 were also strikingly similar to data appearing in other unrelated articles, and western blot data appeared to have been shared between Fig. 6A and E on p. 97, where the results from differently performed experiments were intended to have been portrayed. Owing to the fact that the contentious data in the above article had already been submitted to/published in unrelated articles, and given the fact that Fig. 6 had clearly been assembled incorrectly, the Editor of has decided that this paper should be retracted from the Journal. After having been in contact with the authors, they accepted the decision to retract the paper. The Editor apologizes to the readership for any inconvenience caused. [Oncology Reports 36: 90‑98, 2016; DOI: 10.3892/or.2016.4782].

摘要

在本文发表后,一位关注此事的读者提醒编辑注意,第93页图2C中所示的某些细胞数据已在另一篇由不同研究机构的不同作者撰写的文章中提交给了另一家期刊,该文章随后已被撤回。此外,编辑办公室在对上述论文中的数据进行独立评估时发现,图1和图4中的流式细胞术数据也与其他不相关文章中出现的数据惊人地相似,并且蛋白质印迹数据似乎在第97页的图6A和E之间共享,而这两处本应呈现不同实验的结果。由于上述文章中有争议的数据已提交给/发表在不相关的文章中,并且鉴于图6明显组装错误,《肿瘤学报告》的编辑决定将本文从该期刊撤回。在与作者联系后,他们接受了撤回论文的决定。编辑就所造成的任何不便向读者致歉。[《肿瘤学报告》36: 90 - 98, 2016; DOI: 10.3892/or.2016.4782]

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