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肝门部胆管癌患者机器人手术与腹腔镜手术的短期和长期疗效比较:一项病例对照研究

Comparison of short- and long-term outcomes between robotic and laparoscopic operation in hilar cholangiocarcinoma patients: a case control study.

作者信息

Wang Weihong, Xu Jiawei, Peng Jin, Duan Yunfei, Han Bing, Yue Yang, Zhang Zhiheng, Yu Decai

机构信息

State Key Laboratory of Pharmaceutical Biotechnology, Division of Hepatobiliary and Transplantation Surgery, Department of General Surgery, Affiliated Drum Tower Hospital Clinical College of Jiangsu University, Nanjing, 210008, China.

Division of Hepatobiliary and Transplantation Surgery, Department of General Surgery, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, 210008, China.

出版信息

Surg Endosc. 2025 Jun 13. doi: 10.1007/s00464-025-11742-0.

Abstract

BACKGROUND

Robotic surgery (RS) has gained increasing acceptance due to its ability to overcome certain limitations associated with laparoscopic surgery (LS). However, the performance of RS in hilar cholangiocarcinoma (HCCA) patients compared with LS remain unclear. This study aimed to compare the short- and long-term outcomes of RS versus LS in patients with HCCA.

METHOD

This retrospective study included patients who underwent radical resection of HCCA between February 2020 and August 2024. Baseline characteristics, pathological findings, surgical outcomes, and long-term outcomes were analyzed and compared between the RS and LS group.

RESULTS

The baseline characteristics and pathologic findings of both groups were comparable. The RS group had less estimated blood loss [300 (175-400) vs 700 (200-750) ml, p = 0.008], and lower ALT, AST, TBIL, and DBIL compared to LS group, while no significant differences in postoperative complications. Regarding long-term outcomes, the overall survival rates and recurrence-free survival rates were comparable in two groups (p = 0.77 and p = 0.17, respectively).

CONCLUSION

This study demonstrated that robotic surgery for HCCA generally achieves satisfactory perioperative outcomes compared to laparoscopic surgery. With continued advancements in surgical techniques and accumulation of experience, robotic radical resection for HCCA could become a routine approach in the future.

摘要

背景

机器人手术(RS)因其能够克服与腹腔镜手术(LS)相关的某些局限性而越来越被接受。然而,与LS相比,RS在肝门部胆管癌(HCCA)患者中的表现仍不清楚。本研究旨在比较RS与LS治疗HCCA患者的短期和长期结果。

方法

这项回顾性研究纳入了2020年2月至2024年8月期间接受HCCA根治性切除术的患者。对RS组和LS组的基线特征、病理结果、手术结果和长期结果进行分析和比较。

结果

两组的基线特征和病理结果具有可比性。与LS组相比,RS组的估计失血量较少[300(175 - 400)ml对700(200 - 750)ml,p = 0.008],ALT、AST、TBIL和DBIL较低,而术后并发症无显著差异。关于长期结果,两组的总生存率和无复发生存率具有可比性(分别为p = 0.77和p = 0.17)。

结论

本研究表明,与腹腔镜手术相比,机器人手术治疗HCCA通常能取得令人满意的围手术期结果。随着手术技术的不断进步和经验的积累,机器人根治性切除HCCA在未来可能会成为一种常规方法。

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