John Joel, Konar Subhas, Shukla Dhaval, Salian Neil Manjunath, Srivinias Dwarakanath
Department of Neurosurgery, 2nd Floor Floor (Right Wing), Neurosciences Faculty Center, National Institute of Mental Health and Neuro Sciences, NIMHANS, Dr. MH Marigowda Road, Bengaluru, 560029, Karnataka, India.
Childs Nerv Syst. 2025 Jun 14;41(1):211. doi: 10.1007/s00381-025-06870-w.
While previous studies have focused on qualitative assessments of surgical outcomes, limited research exists on quantitative analysis of intracranial and intraorbital volume changes following surgical correction. This study assesses preoperative and postoperative changes in intracranial and intraorbital volumes in children undergoing craniosynostosis correction surgery.
A retrospective observational imaging study analyzed CT scans of 103 children who underwent craniosynostosis surgery between January 2009 and June 2022. Of these, 44 patients had both preoperative and postoperative CT scans suitable for volumetric assessment. Volumetric analysis was conducted using the Brainlab Elements Planning software, measuring intracranial and intraorbital volumes.
In patients who underwent cranial vault remodeling with orbital advancement, there was a significant increase in intracranial volume (3.85%) and bilateral orbital volumes (right: 8.74%, left: 7.31%; p < 0.001).
A quantitative volumetric analysis demonstrated significant improvements in both intracranial and orbital volumes following craniosynostosis surgery with orbital advancement.
尽管先前的研究集中于手术结果的定性评估，但对于手术矫正后颅内和眶内容积变化的定量分析研究有限。本研究评估接受颅缝早闭矫正手术的儿童术前和术后颅内及眶内容积的变化。
一项回顾性观察性影像学研究分析了2009年1月至2022年6月期间接受颅缝早闭手术的103名儿童的CT扫描。其中，44例患者术前和术后的CT扫描均适合进行容积评估。使用Brainlab Elements Planning软件进行容积分析，测量颅内和眶内容积。
在接受颅骨重塑并伴有眶前移的患者中，颅内容积（3.85%）和双侧眶内容积（右侧：8.74%，左侧：7.31%；p < 0.001）有显著增加。
定量容积分析表明，颅缝早闭伴眶前移手术后颅内和眶内容积均有显著改善。
