Department of Oral and Maxillofacial Surgery, Erasmus Medical Center, Dr Molewaterplein 40, Rotterdam, The Netherlands.
J Craniomaxillofac Surg. 2012 Apr;40(3):223-8. doi: 10.1016/j.jcms.2011.04.005. Epub 2011 Jul 12.
Patients with syndromic craniosynostosis suffering from shallow orbits due to midface hypoplasia can be treated with a Le Fort III advancement osteotomy. This study evaluates the influence of Le Fort III advancement on orbital volume, position of the infra-orbital rim and globe. In pre- and post-operative CT-scans of 18 syndromic craniosynostosis patients, segmentation of the left and right orbit was performed and the infra-orbital rim and globe were marked. By superimposing the pre- and post-operative scans and by creating a reference coordinate system, movements of the infra-orbital rim and globe were assessed. Orbital volume increased significantly, by 27.2% for the left and 28.4% for the right orbit. Significant anterior movements of the left infra-orbital rim of 12.0mm (SD 4.2) and right infra-orbital rim of 12.8mm (SD 4.9) were demonstrated. Significant medial movements of 1.7mm (SD 2.2) of the left globe and 1.5mm (SD 1.9) of the right globe were demonstrated. There was a significant correlation between anterior infra-orbital rim movement and the increase in orbital volume. Significant orbital volume increase has been demonstrated following Le Fort III advancement. The position of the infra-orbital rim was moved forward significantly, whereas the globe position remained relatively unaffected.
由于中面部发育不全导致眼眶浅的综合征性颅缝早闭患者，可以采用 Le Fort III 型上颌骨前移术进行治疗。本研究评估了 Le Fort III 型上颌骨前移术对上眼眶容积、眶下缘位置和眼球位置的影响。在 18 例综合征性颅缝早闭患者的术前和术后 CT 扫描中，对左侧和右侧眼眶进行了分割，并对眶下缘和眼球进行了标记。通过叠加术前和术后扫描，并创建参考坐标系，评估了眶下缘和眼球的运动。左侧眼眶容积增加了 27.2%，右侧眼眶容积增加了 28.4%。左侧眶下缘向前移动了 12.0mm（SD 4.2），右侧眶下缘向前移动了 12.8mm（SD 4.9），这是显著的。左侧眼球向内侧移动了 1.7mm（SD 2.2），右侧眼球向内侧移动了 1.5mm（SD 1.9），这也是显著的。眶下缘向前运动与眼眶容积增加之间存在显著相关性。Le Fort III 型上颌骨前移术后，眼眶容积显著增加。眶下缘位置显著向前移动，而眼球位置相对不受影响。
