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憩室、肿瘤,还是两者皆有?乙状结肠憩室病中癌的早期检测。

Diverticula, neoplasia, or both? Early detection of carcinoma in sigmoid diverticular disease.

作者信息

Boulos P B, Cowin A P, Karamanolis D G, Clark C G

出版信息

Ann Surg. 1985 Nov;202(5):607-9. doi: 10.1097/00000658-198511000-00012.

DOI:10.1097/00000658-198511000-00012
PMID:4051609
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1250975/
Abstract

In 105 patients with symptomatic sigmoid diverticular disease, colonoscopy revealed an associated frequency of carcinoma of seven (6.6%) (Dukes A in 4, B in 2, and C in 1) and adenomas in 29 (27.6%), with a peak incidence of 60 to 79 years and an equal sex distribution. In 45 (43%) examinations, the barium enema was inaccurate. The presenting complaints of abdominal pain and/or alteration in bowel habit in 36 patients with neoplasms and 69 without were similar, but significantly more patients with neoplasms complained of rectal bleeding (p less than 0.05). Endoscopic examination is therefore recommended in patients with sigmoid diverticular disease, particularly in those aged over 60 years and with rectal bleeding.

摘要

在105例有症状的乙状结肠憩室病患者中,结肠镜检查发现同时患有癌的比例为7例(6.6%)(4例为杜克A期,2例为B期,1例为C期),患有腺瘤的比例为29例(27.6%),发病高峰年龄为60至79岁,男女分布均等。在45次(43%)检查中,钡灌肠检查结果不准确。36例患有肿瘤和69例未患肿瘤患者的主要症状腹痛和/或排便习惯改变相似,但患有肿瘤的患者中抱怨直肠出血的明显更多(p<0.05)。因此,建议对乙状结肠憩室病患者进行内镜检查,尤其是60岁以上且有直肠出血的患者。

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本文引用的文献

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SMALL POLYPOID LESIONS ASSOCIATED WITH SPASTIC DIVERTICULOSIS.
Dis Colon Rectum. 1965 Jan-Feb;8:78-84. doi: 10.1007/BF02617055.
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Results of surgery in treatment of cancer of the large intestine.大肠癌手术治疗的结果。
Br Med J. 1957 Apr 6;1(5022):793-6. doi: 10.1136/bmj.1.5022.793.
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Natural history of diverticular disease of the colon. A review of 521 cases.结肠憩室病的自然史。521例病例回顾。
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