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非精子细胞主要源于精子发生过程吗?对106名生育能力正常和102名生育能力低下男性的研究。

Do non-spermatozoal cells mainly stem from spermiogenesis? Study of 106 fertile and 102 subfertile men.

作者信息

Auroux M, Collin C, Couvillers M L

出版信息

Arch Androl. 1985;14(1):73-80. doi: 10.3109/01485018508987281.

DOI:10.3109/01485018508987281
PMID:4051631
Abstract

The various non-spermatozoal cell types in the semen of 106 fertile (F) and 102 subfertile (SF) men were described and their relative proportions estimated. About 94% (F) and 90% (SF) were found to be germinal elements, among which, respectively, about 27% and 51% were spermatids, 48% and 36% residual bodies, 19.4% and 2.6% primary spermatocytes, 0.03% and 0.61% spermatogonia. The epithelial cells and blood cells represented about 6% (F) and 10% (SF) of the non-spermatozoal cells; in F men 5.3% and in SF men 9.5% were found to be polymorphonuclear leucocytes. In SF men the predominance of spermatids might be due to a particular fragility of spermiogenesis. To the three stages of spermatogenesis-the gonial multiplication, meiosis, and spermiogenesis-might correspond three specific pathologies. A pathology of the very germ cell production was thus suggested, as well as a pathology of the means by which the final product would be controlled. The Sertoli cell was supposed to be mainly involved in the latter process.

摘要

对106名生育能力正常(F)和102名生育能力低下(SF)男性精液中的各种非精子细胞类型进行了描述,并估计了它们的相对比例。发现约94%(F组)和90%(SF组)为生殖细胞成分,其中,精子细胞分别约占27%和51%,残余体占48%和36%,初级精母细胞占19.4%和2.6%,精原细胞占0.03%和0.61%。上皮细胞和血细胞分别占非精子细胞的约6%(F组)和10%(SF组);在F组男性中,5.3%为多形核白细胞,在SF组男性中,9.5%为多形核白细胞。在SF组男性中,精子细胞占优势可能是由于精子发生过程中存在特殊的脆弱性。精子发生的三个阶段——精原细胞增殖、减数分裂和精子形成——可能对应三种特定的病理情况。因此,提示存在生殖细胞产生方面的病理情况,以及最终产物调控方式的病理情况。推测支持细胞主要参与后一过程。

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引用本文的文献

1
RNA and protein synthesis in the nonspermatozoal cells of normal human semen.正常人类精液中非精子细胞中的RNA和蛋白质合成
J Anat. 1996 Feb;188 ( Pt 1)(Pt 1):137-47.