Oeffinger Donna J, Iwinski Henry, Talwalkar Vishwas, Roberto Rolando, Dueber David, Bagley Anita
Shriners Children's Lexington, 110 Conn Terrace, Lexington, KY, 40508, USA.
Shriners Children's Northern California, Sacramento, CA, USA.
Spine Deform. 2025 Jun 14. doi: 10.1007/s43390-025-01120-0.
Using patient-reported questionnaires (PROs), the impact of adolescent idiopathic scoliosis (AIS) on psychosocial well-being domains of Self-Image, Self-Esteem, Mental Health and Peer Relationships, and the interplay between these domains, physical function and clinical measures was investigated.
95 patients from a convenience cohort with AIS completed questionnaires (SRS-22r, SAQ, PODCI, PROMIS, and Harter's Self-Perception Profile), and clinical data were collected. PRO scores analyses included descriptive statistics, unpaired t-test comparing typical peers and correlations. Scores on PRO domains for the lowest interquartile groups (LowIQR) were compared with the Remaining Cohorts (RC) using t tests, and differences were evaluated using Cohen's d statistic.
The entire study cohort reported psychosocial well-being similar to their AIS and typical peers. Scores on PsychoSocial Self-Image measures and PODCI Happiness, a mental health domain, and physical function measures of PODCI Transfer&Mobility and Sports&Physical Function were worse than typical population. Curve severity and clinical measures were not linked to PRO scores. For LowIQR patients, scores were statistically worse than the RCs in many domains with effect sizes indicating clinically noticeable differences. Patients in LowIQRgroups reported scores below typical peers on Mental Health, Self-Esteem and global self-image measures, while RC did not.
This research enhances the clinical utility of PROs for assessing psychosocial well-being in patients with AIS by establishing thresholds for identification of patients reporting scores worse than their AIS peers. Interventions targeting psychosocial well-being may help mitigate the potential negative impact of scoliosis on adolescents.
使用患者报告问卷（PROs），研究青少年特发性脊柱侧凸（AIS）对自我形象、自尊、心理健康和同伴关系等心理社会幸福感领域的影响，以及这些领域、身体功能和临床指标之间的相互作用。
来自便利队列的95例AIS患者完成了问卷（SRS - 22r、SAQ、PODCI、PROMIS和哈特自我认知量表），并收集了临床数据。PRO分数分析包括描述性统计、比较典型同龄人组的非配对t检验以及相关性分析。使用t检验比较最低四分位数组（LowIQR）的PRO领域得分与其余队列（RC），并使用科恩d统计量评估差异。
整个研究队列报告的心理社会幸福感与他们的AIS患者和典型同龄人相似。心理社会自我形象测量得分、心理健康领域的PODCI幸福感得分以及PODCI转移与活动能力和运动与身体功能的身体功能测量得分均低于一般人群。曲线严重程度和临床指标与PRO分数无关。对于LowIQR患者，在许多领域得分在统计学上比RC更差，效应大小表明存在临床上明显的差异。LowIQR组患者在心理健康、自尊和整体自我形象测量方面的得分低于典型同龄人，而RC组则没有。
本研究通过确定识别得分低于其AIS同龄人患者的阈值，提高了PROs在评估AIS患者心理社会幸福感方面的临床效用。针对心理社会幸福感的干预措施可能有助于减轻脊柱侧凸对青少年的潜在负面影响。
