• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

诊断准确性研究中样本量估计用户指南。

User's guide to sample size estimation in diagnostic accuracy studies.

作者信息

Akoglu Haldun

机构信息

Department of Emergency Medicine, Marmara University School of Medicine, Istanbul, Turkey.

出版信息

Turk J Emerg Med. 2022 Sep 30;22(4):177-185. doi: 10.4103/2452-2473.357348. eCollection 2022 Oct-Dec.

DOI:10.4103/2452-2473.357348
PMID:36353389
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9639742/
Abstract

Sample size estimation is an overlooked concept and rarely reported in diagnostic accuracy studies, primarily because of the lack of information of clinical researchers on when and how they should estimate sample size. In this review, readers will find sample size estimation procedures for diagnostic tests with dichotomized outcomes, explained by clinically relevant examples in detail. We hope, with the help of practical tables and a free online calculator (https://turkjemergmed.com/calculator), researchers can estimate accurate sample sizes without a need to calculate from equations, and use this review as a practical guide to estimating sample size in diagnostic accuracy studies.

摘要

样本量估计是一个被忽视的概念，在诊断准确性研究中很少被报告，主要原因是临床研究人员缺乏关于何时以及如何估计样本量的信息。在本综述中，读者将通过详细的临床相关示例找到用于二分结果诊断测试的样本量估计程序。我们希望，借助实用表格和免费在线计算器（https://turkjemergmed.com/calculator），研究人员无需根据公式进行计算就能估计出准确的样本量，并将本综述作为诊断准确性研究中估计样本量的实用指南。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb55/9639742/20042f5b1680/TJEM-22-177-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb55/9639742/20042f5b1680/TJEM-22-177-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb55/9639742/20042f5b1680/TJEM-22-177-g001.jpg

相似文献

1
User's guide to sample size estimation in diagnostic accuracy studies.诊断准确性研究中样本量估计用户指南。
Turk J Emerg Med. 2022 Sep 30;22(4):177-185. doi: 10.4103/2452-2473.357348. eCollection 2022 Oct-Dec.
2
Determining Sample Size for Accurate Estimation of the Squared Multiple Correlation Coefficient.确定用于准确估计复相关系数平方的样本量。
Multivariate Behav Res. 2000 Jan 1;35(1):119-37. doi: 10.1207/S15327906MBR3501_5.
3
Sample size estimation in diagnostic test studies of biomedical informatics.生物医学信息学诊断试验研究中的样本量估计。
J Biomed Inform. 2014 Apr;48:193-204. doi: 10.1016/j.jbi.2014.02.013. Epub 2014 Feb 26.
4
Bayesian sample size determination for prevalence and diagnostic test studies in the absence of a gold standard test.在没有金标准检测的情况下，用于患病率和诊断试验研究的贝叶斯样本量确定
Biometrics. 2004 Jun;60(2):388-97. doi: 10.1111/j.0006-341X.2004.00183.x.
5
Practical sample size calculations for surveillance and diagnostic investigations.监测和诊断研究的实用样本量计算
J Vet Diagn Invest. 2009 Jan;21(1):3-14. doi: 10.1177/104063870902100102.
6
Prediction accuracy of a sample-size estimation method for ROC studies.ROC 研究样本量估计方法的预测准确性。
Acad Radiol. 2010 May;17(5):628-38. doi: 10.1016/j.acra.2010.01.007.
7
8
Translational Metabolomics of Head Injury: Exploring Dysfunctional Cerebral Metabolism with Ex Vivo NMR Spectroscopy-Based Metabolite Quantification头部损伤的转化代谢组学：基于体外核磁共振波谱的代谢物定量分析探索脑代谢功能障碍
9
Ultrasound for diagnosis of birth weight discordance in twin pregnancies.超声在双胎妊娠胎儿体重不一致诊断中的应用。
Cochrane Database Syst Rev. 2021 Mar 9;3(3):CD012553. doi: 10.1002/14651858.CD012553.pub2.
10
Bayesian sample size for diagnostic test studies in the absence of a gold standard: Comparing identifiable with non-identifiable models.无金标准诊断试验研究的贝叶斯样本量：可识别与不可识别模型的比较。
Stat Med. 2010 Nov 20;29(26):2688-97. doi: 10.1002/sim.4037.

引用本文的文献

1
The father's singing voice may impact premature infants' brain more than their mother's: A NICU single-arm exploratory study protocol and preliminary data on a singing and EEG framework based on the fundamental frequency of voice and kinship.父亲的歌声可能比母亲的歌声对早产儿大脑的影响更大：一项新生儿重症监护病房单臂探索性研究方案以及基于嗓音基频和亲属关系的歌唱与脑电图框架的初步数据。
PLoS One. 2025 Aug 14;20(8):e0328211. doi: 10.1371/journal.pone.0328211. eCollection 2025.
2
Pain in individuals with adolescent idiopathic scoliosis: prevalence and association with physical function and psychosocial well-being using patient-reported outcome measures.青少年特发性脊柱侧凸患者的疼痛：采用患者报告结局指标评估其患病率以及与身体功能和心理社会幸福感的关联
Spine Deform. 2025 Aug 14. doi: 10.1007/s43390-025-01121-z.
3

本文引用的文献

1
Blinded sample size re-estimation in a comparative diagnostic accuracy study.比较诊断准确性研究中的盲法样本量重新估计
BMC Med Res Methodol. 2022 Apr 19;22(1):115. doi: 10.1186/s12874-022-01564-2.
2
Introduction to diagnostic test accuracy studies.诊断试验准确性研究简介。
Eur J Endocrinol. 2021 Feb;184(2):E5-E9. doi: 10.1530/EJE-20-1239.
3
Computed tomography for diagnosis of acute appendicitis in adults.成人急性阑尾炎诊断的计算机断层扫描
The diagnostic accuracy of the ESC 0/1-hour algorithm in non-ST-segment elevation myocardial infarction in a crowded emergency department: a real-world experience from a single-center in Türkiye.ESC 0/1小时算法在拥挤急诊科对非ST段抬高型心肌梗死的诊断准确性：土耳其一家单中心的真实世界经验
BMC Emerg Med. 2025 Jul 16;25(1):129. doi: 10.1186/s12873-025-01289-7.
4
Quadratus lumborum muscle stiffness in chronic non-specific low back pain: a diagnostic accuracy study.慢性非特异性下背痛患者腰方肌僵硬情况：一项诊断准确性研究
Eur Spine J. 2025 Jul 8. doi: 10.1007/s00586-025-09114-2.
5
Use of brief, simple anxiety assessment tools in palliative care - yes, we can: a cross-sectional observational study of anxiety visual analog scale and numeric rating scale.在姑息治疗中使用简短、简单的焦虑评估工具——是的，我们可以：焦虑视觉模拟量表和数字评定量表的横断面观察研究
BMC Palliat Care. 2025 Jul 1;24(1):173. doi: 10.1186/s12904-025-01814-2.
6
Comparison of machine learning and human prediction to identify trauma patients in need of hemorrhage control resuscitation (ShockMatrix study): a prospective observational study.机器学习与人工预测用于识别需要出血控制复苏的创伤患者的比较（休克矩阵研究）：一项前瞻性观察性研究。
Lancet Reg Health Eur. 2025 Jun 12;55:101340. doi: 10.1016/j.lanepe.2025.101340. eCollection 2025 Aug.
7
Examining the impact of adolescent idiopathic scoliosis on psychosocial well-being and physical function: revealing insights from patient-reported outcomes.探讨青少年特发性脊柱侧弯对心理社会幸福感和身体功能的影响：从患者报告结局中揭示见解。
Spine Deform. 2025 Jun 14. doi: 10.1007/s43390-025-01120-0.
8
Performance of malaria rapid diagnostic test, microscopy, polymerase chain reaction, and histopathology to diagnose malaria among pregnant and parturient women using peripheral, placental, and cord blood, and placental biopsy in Majang Zone of Gambella Region, Southwest Ethiopia.在埃塞俄比亚西南部甘贝拉地区马江区，使用外周血、胎盘血、脐带血以及胎盘活检，对疟疾快速诊断检测、显微镜检查、聚合酶链反应和组织病理学在诊断孕妇和产妇疟疾方面的性能进行研究。
Malar J. 2025 Jun 1;24(1):175. doi: 10.1186/s12936-025-05426-2.
9
Discriminability of the Beck Depression Inventory and its Abbreviations in an Adolescent Psychiatric Sample.贝克抑郁量表及其缩写在青少年精神病样本中的可辨别性。
Scand J Child Adolesc Psychiatr Psychol. 2025 Apr 25;13(1):9-21. doi: 10.2478/sjcapp-2025-0002. eCollection 2025 Jan.
10
Evaluation of the Rapid Urease Test (RUT) Device for Rapid Diagnosis of in Middle-Aged and Elderly Taiwanese Patients.用于台湾中老年患者快速诊断的快速尿素酶试验（RUT）装置的评估
Microorganisms. 2025 Mar 28;13(4):767. doi: 10.3390/microorganisms13040767.
Cochrane Database Syst Rev. 2019 Nov 19;2019(11):CD009977. doi: 10.1002/14651858.CD009977.pub2.
4
Development of practical recommendations for diagnostic accuracy studies in low-prevalence situations.制定适用于低患病率情况下诊断准确性研究的实用建议。
J Clin Epidemiol. 2019 Oct;114:38-48. doi: 10.1016/j.jclinepi.2019.05.018. Epub 2019 May 28.
5
Sample size estimation in diagnostic test studies of biomedical informatics.生物医学信息学诊断试验研究中的样本量估计。
J Biomed Inform. 2014 Apr;48:193-204. doi: 10.1016/j.jbi.2014.02.013. Epub 2014 Feb 26.
6
Sample size in studies on diagnostic accuracy in ophthalmology: a literature survey.眼科诊断准确性研究中的样本量：一项文献调查。
Br J Ophthalmol. 2007 Jul;91(7):898-900. doi: 10.1136/bjo.2006.113290. Epub 2007 Feb 14.
7
Sample sizes of studies on diagnostic accuracy: literature survey.诊断准确性研究的样本量：文献调查。
BMJ. 2006 May 13;332(7550):1127-9. doi: 10.1136/bmj.38793.637789.2F. Epub 2006 Apr 20.
8
An introduction to power and sample size estimation.功效与样本量估计简介。
Emerg Med J. 2003 Sep;20(5):453-8. doi: 10.1136/emj.20.5.453.
9
Sample size calculations in studies of test accuracy.检验准确性研究中的样本量计算。
Stat Methods Med Res. 1998 Dec;7(4):371-92. doi: 10.1177/096228029800700405.
10
Statistical methodology: I. Incorporating the prevalence of disease into the sample size calculation for sensitivity and specificity.统计方法：I. 将疾病患病率纳入灵敏度和特异度样本量计算中。
Acad Emerg Med. 1996 Sep;3(9):895-900. doi: 10.1111/j.1553-2712.1996.tb03538.x.