Nikitin A I
Arkh Anat Gistol Embriol. 1985 Aug;89(8):5-17.
The results obtained for the last decades on the problem of early differentiation of mammalian gonads are elucidated. The data on the role of different tissue sources in origin of somatic elements in sex gonads are critically estimated. New data on participation of meiosis-regulating substances (that are produced by the mesonephros and its derivatives) in processes initiating and inhibiting meiosis are presented. The matters on the character of interrelations between the histostructural organization of embryonic gonads and their steroidsynthetic activity are considered. The modern notions on histogenesis of hormonally active stromal elements of the gonads are reported. The role of the data discussed for further investigation of pathogenesis of development of sex anomalies, of disorders in human reproductive function is regarded, as well as that for revealing histogenesis of gonadal tumours.
阐述了过去几十年在哺乳动物性腺早期分化问题上取得的成果。批判性地评估了不同组织来源在性腺体细胞成分起源中的作用的数据。介绍了关于减数分裂调节物质（由中肾及其衍生物产生）参与启动和抑制减数分裂过程的新数据。探讨了胚胎性腺的组织结构组织与其类固醇合成活性之间相互关系的性质问题。报告了关于性腺激素活性基质成分组织发生的现代观念。讨论了所提及的数据在进一步研究性异常发育的发病机制、人类生殖功能障碍方面的作用，以及在揭示性腺肿瘤组织发生方面的作用。
