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[心肌细胞肌原纤维变化的形态学类型]

[Morphological types of the changes in the myofibrils of cardiac muscle cells].

作者信息

Tsellarius Iu G, Semenova L A, Nepomniashchikh L M

出版信息

Arkh Patol. 1980;42(12):3-13.

PMID:7011271
Abstract

Light microscopy and electron microscopy examinations showed the changes in myofibrils to be a criterion of early stages of cardiomyocyte involvement. Proceeding from this, the main types of acute cardiomyocyte damage are distinguished: contractures (segmentary and subsegmentary), primary clump degeneration, intracellular myocytolysis and cytolysis. The best way to detect the state of myofibrils by light microscopy is to use polarization microscopy which diagnoses in sections acute metabolic damages and early stages of myocardial infarction, repeated and relapsing infarctions, fibrillation of ventricles. The utilization of polarization microscopy in pathological practice permits one to diagnose definitely the early stages of acute damages of the heart in cases of sudden and unexpected death.

摘要

光学显微镜和电子显微镜检查显示,肌原纤维的变化是心肌细胞受累早期阶段的一个标准。据此,可区分急性心肌细胞损伤的主要类型:挛缩(节段性和亚节段性)、原发性团块状变性、细胞内肌细胞溶解和细胞溶解。通过光学显微镜检测肌原纤维状态的最佳方法是使用偏光显微镜,它可在切片中诊断急性代谢损伤以及心肌梗死的早期阶段、反复性和复发性梗死、心室颤动。在病理实践中使用偏光显微镜可以明确诊断猝死病例中心脏急性损伤的早期阶段。

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