Krymskiĭ L D, Mozhina A A
Arkh Patol. 1985;47(6):29-36.
Failure of the bicuspid valve is one of the most frequent (20-25%) and grave complications of myocardial infarction. The causes of mitral failure occurring at different times following myocardial infarction are established. It is shown that the severity of coronary arteries lesions in postinfarction mitral failure is chiefly due to the occlusion of the two or three coronary arteries and to the segmental stenosis of more than 75% of the lumen of the main heart arteries. Postinfarction mitral failure caused by dysfunction of the papillary muscles may be provoked by acute infarction of the papillary muscles, rupture of the papillary muscle body, large-focal papillary muscle cardiosclerosis, by dilation of the left ventricular cavity and fibrous ring resulting in disturbance of space interrelationships between the tendinous filaments and valves.
二尖瓣功能不全是心肌梗死最常见（20%-25%）且严重的并发症之一。心肌梗死后不同时间发生二尖瓣功能不全的原因已明确。结果显示，梗死后二尖瓣功能不全时冠状动脉病变的严重程度主要归因于两支或三支冠状动脉闭塞以及主要心脏动脉管腔75%以上的节段性狭窄。由乳头肌功能障碍引起的梗死后二尖瓣功能不全可能由乳头肌急性梗死、乳头肌主体破裂、大片局灶性乳头肌心肌硬化、左心室腔和纤维环扩张导致腱索与瓣膜之间空间相互关系紊乱引发。
