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[小儿急性化脓性阑尾炎的可视内镜逆行阑尾炎治疗的治疗价值]

[Therapeutic value of visual endoscopic retrograde appendicitis therapy in children with acute suppurative appendicitis].

作者信息

Zhang A D, Fan N, Wang M Z, Zeng L C, Wang C H, Lin Y, Zhou J R, Song Y P, Zhang N N, Wang H Y, Guo H W, Zhou Y, Wang B X, Jiang X

机构信息

Department of Pediatrics, Tangdu Hospital of Air Force Medical University, Xi'an 710038, China.

出版信息

Zhonghua Er Ke Za Zhi. 2025 Jul 2;63(7):754-758. doi: 10.3760/cma.j.cn112140-20250304-00173.

Abstract

To investigate the therapeutic value of visual endoscopic retrograde appendicitis therapy (vERAT) in pediatric patients with acute suppurative appendicitis (ASA). This was a retrospective cohort study. A total of 55 ASA patients who underwent vERAT at the Pediatric Department of the Tangdu Hospital of Air Force Medical University between November 2023 and January 2025 were selected and divided into groups based on the presence or absence of fecaliths: fecalith group and non-fecalith group. The baseline characteristics, initial treatment success rates, treatment costs, hospital stay duration, procedure time, and recurrence rates between two groups were compared. Mann-Whitney test and test were used to evaluate group differences. A total of 55 ASA patients were enrolled, including 38 males and 17 females, with the age of 11.2 (9.2, 13.1) years. Based on the presence of fecaliths, patients were divided into two groups: fecalith group (32 cases) and non-fecalith group (23 cases). No statistically significant differences were observed between the two groups in terms of age, gender, duration of abdominal pain, white blood cell count, neutrophil percentage, diameter of appendix, thickness of appendix clinical symptoms or signs (all >0.05). The initial treatment success rates were 91% (29/32) in fecalith group and 96% (22/23) in non-fecalith group, with no statistically significant difference (=0.632). However, significant differences were noted in stent placement (=5.85, =0.026) and procedure time (=4.75, <0.001). The follow-up duration time was 6.0 (2.0, 12.0) and 7.0 (2.0, 8.5) months for the fecalith and non-fecalith groups, respectively, with no significant difference (=0.05, =0.962). The recurrence rates were 14% (4/29) in fecalith group and 5% (1/22) in non-fecalith group, with no statistically significant difference (=0.375). vERAT can safely and effectively treat pediatric ASA, regardless of the presence or absence of fecaliths. It can provide a new treatment option for ASA.

摘要

探讨直视下内镜逆行阑尾炎治疗术(vERAT)在小儿急性化脓性阑尾炎(ASA)患者中的治疗价值。这是一项回顾性队列研究。选取2023年11月至2025年1月在空军军医大学唐都医院儿科接受vERAT治疗的55例ASA患者,根据是否存在粪石分为粪石组和非粪石组。比较两组患者的基线特征、初始治疗成功率、治疗费用、住院时间、手术时间及复发率。采用Mann-Whitney检验和检验评估组间差异。共纳入55例ASA患者,其中男性38例,女性17例,年龄11.2(9.2,13.1)岁。根据是否存在粪石,将患者分为两组:粪石组(32例)和非粪石组(23例)。两组患者在年龄、性别、腹痛持续时间、白细胞计数、中性粒细胞百分比、阑尾直径、阑尾厚度、临床症状或体征方面均无统计学差异(均>0.05)。粪石组初始治疗成功率为91%(29/32),非粪石组为96%(22/23),差异无统计学意义(=0.632)。然而,在支架置入(=5.85,=0.026)和手术时间(=4.75,<0.001)方面存在显著差异。粪石组和非粪石组的随访时间分别为6.0(2.0,12.0)个月和7.0(2.0,8.5)个月,差异无统计学意义(=0.05,=0.962)。粪石组复发率为14%(4/29),非粪石组为5%(1/22),差异无统计学意义(=0.375)。vERAT可安全有效地治疗小儿ASA,无论是否存在粪石。它可为ASA提供一种新的治疗选择。

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