Ghashghaei Negar, Rashki Kemmak Asma, Goli Elham, Shishebor Astaneh Shima, Dahri Monir, Mazaheri Habibi Mohammad Reza
Department of Nutrition Sciences, Varastegan Institute for Medical Sciences, Mashhad, Iran.
Student Research Committee, Varastegan Institute for Medical Sciences, Mashhad, Iran.
J Health Popul Nutr. 2025 Jun 15;44(1):200. doi: 10.1186/s41043-025-00953-9.
The human gut microbiota performs a variety of essential physiological homeostasis functions, including the development of the immune system, nutrient synthesis, vitamin production, and energy metabolism. Ginger's extensive pharmacological actions include anti-inflammatory, antioxidant, hypoglycemic, and lipid-lowering effects. This study aimed to investigate the beneficial effects of ginger on the prevention of obesity through the modulation of gut microbiota.
This study was carried out as a systematic review in 2024 by searching on the reliable databases of PubMed, Web of Sciences, and Scopus using the keywords "Obesity", "Gut-Microbiota", "Ginger" and their MeSH were analyzed with no time limit. Articles published in English that specifically focused on the beneficial effects of ginger in the prevention of obesity through the modulation of gut microbiota were included. Abstracts, letters to the editor, protocols, review articles and studies were inaccessible were excluded from consideration. To assess the quality of the included studies, a tool comprising 10 items was developed.
Generally, 3192 papers were retrieved from the above-mentioned databases and nine papers were considered for the present study after reading titles and abstracts and by considering the inclusion and exclusion criteria. In all these studies, the impact of ginger on gut microbiota has been examined, with a consistent focus on its effects on obesity. Overall, the existing evidence suggests that ginger not only positively influences gut microbiota but also serves as an effective agent in the prevention and management of obesity.
These findings highlight the potential of ginger as a natural and effective option in obesity management programs and for improving overall health. Nonetheless, it is clear that the amount of ginger ingested may influence its effects, and more research is required to establish the proper dosage and understand the exact how ginger supplementation works.
人类肠道微生物群执行多种基本的生理稳态功能，包括免疫系统发育、营养合成、维生素产生和能量代谢。生姜具有广泛的药理作用，包括抗炎、抗氧化、降血糖和降脂作用。本研究旨在通过调节肠道微生物群来探讨生姜对预防肥胖的有益作用。
本研究于2024年进行系统评价，通过在PubMed、Web of Sciences和Scopus等可靠数据库中搜索关键词“肥胖”、“肠道微生物群”、“生姜”，并对其医学主题词进行分析，无时间限制。纳入以英文发表的、专门关注生姜通过调节肠道微生物群预防肥胖有益作用的文章。排除摘要、给编辑的信、方案、综述文章以及无法获取的研究。为评估纳入研究的质量，开发了一个包含10项内容的工具。
一般来说，从上述数据库中检索到3192篇论文，在阅读标题和摘要并考虑纳入和排除标准后，本研究纳入了9篇论文。在所有这些研究中，均考察了生姜对肠道微生物群的影响，且一致关注其对肥胖的影响。总体而言，现有证据表明生姜不仅对肠道微生物群有积极影响，而且是预防和管理肥胖的有效药物。
这些发现凸显了生姜作为肥胖管理计划中天然有效选择以及改善整体健康的潜力。尽管如此，很明显摄入生姜的量可能会影响其效果，需要更多研究来确定合适的剂量并了解补充生姜的确切作用机制。
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