Eilers-Petri Caroline, Oberhagemann Annika, Mäurer Mathias
Klinik für Neurologie und neurologische Frührehabilitation, Klinikum Würzburg Mitte gGmbH, Salvatorstraße 7, 97070, Würzburg, Deutschland.
Schmerz. 2024 Jun;38(3):221-230. doi: 10.1007/s00482-024-00808-y. Epub 2024 Apr 19.
Polyneuropathy is a disease of the peripheral nervous system that usually results in distally emphasized, often symmetrical sensory and motor stimulation and deficits. These are often extremely painful. They can be divided into hereditary and acquired causes; inflammatory and infectious causes should be further differentiated among the acquired causes. A careful diagnostic workup is essential. Clinical signs and distribution patterns of symptoms can often already provide clues to the underlying aetiology. This review describes this workup, which in addition to the medical history and clinical examination always includes thorough laboratory diagnostics, electrophysiological examination and cerebrospinal fluid diagnostics. In individual cases, further diagnostic steps may be necessary in order to make the correct diagnosis.
多发性神经病是一种周围神经系统疾病，通常导致以远端为主的、常为对称性的感觉和运动功能障碍及缺损。这些症状往往极为疼痛。可分为遗传性和后天性病因；后天性病因中应进一步区分炎症性和感染性病因。仔细的诊断检查至关重要。临床体征和症状分布模式常常能为潜在病因提供线索。本综述描述了这一诊断检查过程，除病史和临床检查外，其始终包括全面的实验室诊断、电生理检查和脑脊液诊断。在个别情况下，可能需要进一步的诊断步骤以做出正确诊断。
