Puczynski M S, Ow E P, Rust C
Arch Otolaryngol. 1985 Nov;111(11):768-9. doi: 10.1001/archotol.1985.00800130100015.
A 30-month-old female infant had a cardiopulmonary arrest due to viscous lidocaine. The protective airway mechanisms were blunted by this drug, resulting in aspiration, hypoxia, seizures, and death. Lidocaine has also been associated with respiratory depression, psychosis, methemoglobinemia, and toxic cardiovascular reactions. We do not recommend the use of viscous lidocaine for minor oral irritation in infants and young children.
一名30个月大的女婴因使用粘性利多卡因而发生心肺骤停。这种药物削弱了气道保护机制,导致误吸、缺氧、癫痫发作和死亡。利多卡因还与呼吸抑制、精神病、高铁血红蛋白血症和毒性心血管反应有关。我们不建议在婴幼儿中使用粘性利多卡因来治疗轻微的口腔刺激。