MacNevin Wyatt, Bethune Ainsley, Wang Cheng, Cox Ashley
Department of Urology, Dalhousie University, Halifax, CAN.
Department of Family Medicine, Dalhousie University, Halifax, CAN.
Cureus. 2025 May 14;17(5):e84096. doi: 10.7759/cureus.84096. eCollection 2025 May.
Bladder amyloidosis is a rare condition of insoluble extracellular protein deposition in the urinary bladder arising as a complication of underlying inflammation and immune dyscrasia. Diagnosis of bladder amyloidosis is done through cystoscopy and evidence of amyloid deposition on pathologic evaluation. Here, we present a case of secondary bladder amyloidosis presenting with acute urinary retention. After ruling out bladder malignancy, the patient was managed with suprapubic catheterization after failing beta-3 agonist therapy and clean intermittent catheterization.
膀胱淀粉样变性是一种罕见的疾病,表现为不溶性细胞外蛋白质在膀胱内沉积,是潜在炎症和免疫失调的并发症。膀胱淀粉样变性的诊断通过膀胱镜检查以及病理评估中淀粉样沉积的证据来进行。在此,我们报告一例以急性尿潴留为表现的继发性膀胱淀粉样变性病例。排除膀胱恶性肿瘤后,患者在β-3激动剂治疗及清洁间歇性导尿失败后,接受了耻骨上膀胱造瘘术治疗。