Caldamone A A, Elbadawi A, Moshtagi A, Frank I N
Urology. 1980 Feb;15(2):174-80. doi: 10.1016/0090-4295(80)90416-1.
Primary localized amyloidosis of the bladder is rare. Two new cases are presented, and 44 cases from the literature are reviewed. The disease tends to occur in a younger age group in men than in women. It presents most frequently with gross painless hematuria, and usually appears at cystoscopy as a tumefied, yellowish, and occasionally ulcerated lesion. The amyloid deposits usually involve suburothelial connective tissue, suburothelial vessels, and less markedly the vesical muscularis. The treatment varies from transurethral resection to total cystectomy with urinary diversion. Transurethral resection appears to be the treatment of choice, if feasible. Close follow-up of the patient is necessary because of the frequency of multiple recurrences, which may require an ablative procedure.
膀胱原发性局限性淀粉样变性罕见。本文报告2例新病例，并复习文献中的44例。该疾病在男性中发病年龄较女性轻。最常见的表现为无痛肉眼血尿，膀胱镜检查时通常表现为肿胀、发黄、偶有溃疡的病变。淀粉样沉积物通常累及膀胱上皮下结缔组织、膀胱上皮下血管，膀胱肌层受累较轻。治疗方法从经尿道切除术到膀胱全切并尿流改道不等。如果可行，经尿道切除术似乎是首选治疗方法。由于复发频繁，可能需要进行切除手术，因此对患者进行密切随访很有必要。
