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Thrombotic Microangiopathy After Kidney Pancreas Transplant Managed With Eculizumab and a Calcineurin Inhibitor-free Basiliximab/Belatacept Maintenance Regimen: Between a Rock and a Hard Place.

作者信息

Chen Jeanne M, Yaqub Muhammad S, Jan Muhammad Y, Sharfuddin Asif A, Powelson John A, Lutz Andrew J, Hata Jessica L, Fridell Jonathan A

机构信息

Department of Pharmacy, IU Health, Indianapolis, IN.

Department of Surgery, Indiana University School of Medicine, Indianapolis, IN.

出版信息

Transplant Direct. 2025 Jun 12;11(7):e1825. doi: 10.1097/TXD.0000000000001825. eCollection 2025 Jul.

DOI:10.1097/TXD.0000000000001825
PMID:40519672
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12165658/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7df2/12165658/e15a13b44d06/txd-11-e1825-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7df2/12165658/789860a0e0ea/txd-11-e1825-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7df2/12165658/b52e8ee658aa/txd-11-e1825-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7df2/12165658/e15a13b44d06/txd-11-e1825-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7df2/12165658/789860a0e0ea/txd-11-e1825-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7df2/12165658/b52e8ee658aa/txd-11-e1825-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7df2/12165658/e15a13b44d06/txd-11-e1825-g003.jpg

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Thrombotic Microangiopathy After Kidney Pancreas Transplant Managed With Eculizumab and a Calcineurin Inhibitor-free Basiliximab/Belatacept Maintenance Regimen: Between a Rock and a Hard Place.肾胰联合移植后血栓性微血管病采用依库珠单抗及无钙调神经磷酸酶抑制剂的巴利昔单抗/贝拉西普维持方案治疗:进退两难。
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本文引用的文献

1
Safety and Efficacy of Belatacept in Pancreas Transplantation: A Case Series.贝拉西普在胰腺移植中的安全性和有效性:病例系列
Clin Transplant. 2025 Mar;39(3):e70131. doi: 10.1111/ctr.70131.
2
Post-transplant Thrombotic Microangiopathy.移植后血栓性微血管病
J Am Soc Nephrol. 2025 May 1;36(5):940-951. doi: 10.1681/ASN.0000000645. Epub 2025 Jan 31.
3
The Use of Long-Term Monthly Basiliximab Infusions as Rescue Maintenance Immunosuppression in Pancreas Transplant Recipients.长期每月使用巴利昔单抗输注作为胰腺移植受者的挽救维持免疫抑制治疗
Clin Transplant. 2024 Dec;38(12):e70050. doi: 10.1111/ctr.70050.
4
Belatacept in Pancreas Transplantation: Promising Insights From a Cohort Series.贝拉西普在胰腺移植中的应用:来自队列研究系列的有前景的见解。
Transpl Int. 2024 Apr 16;37:12778. doi: 10.3389/ti.2024.12778. eCollection 2024.
5
Belatacept Rescue Therapy in the Early Period After Simultaneous Kidney-Pancreas Transplantation.肾胰联合移植术后早期的贝拉西普挽救治疗
Transpl Int. 2024 Apr 11;37:12628. doi: 10.3389/ti.2024.12628. eCollection 2024.
6
Thrombotic microangiopathy after kidney transplantation: Expanding etiologic and pathogenetic spectra.肾移植后的血栓性微血管病:病因和发病机制范围的扩展
World J Transplant. 2024 Mar 18;14(1):90277. doi: 10.5500/wjt.v14.i1.90277.
7
TMA in Kidney Transplantation.肾移植中的组织微阵列分析
Transplantation. 2023 Nov 1;107(11):2329-2340. doi: 10.1097/TP.0000000000004585. Epub 2023 Oct 21.
8
Pancreas transplantation would be easy if the recipients were not diabetic: A practical guide to post-operative management of diabetic complications in pancreas transplant recipients.如果受者没有糖尿病,胰腺移植将会很容易:胰腺移植受者术后糖尿病并发症处理实用指南。
Clin Transplant. 2021 May;35(5):e14270. doi: 10.1111/ctr.14270. Epub 2021 Mar 11.
9
Contrast-Enhanced Ultrasound Versus Doppler Ultrasound for Detection of Early Vascular Complications of Pancreas Grafts.对比增强超声与多普勒超声在胰腺移植物早期血管并发症检测中的比较
AJR Am J Roentgenol. 2020 Nov;215(5):1093-1097. doi: 10.2214/AJR.20.22858. Epub 2020 Sep 22.
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Am J Transplant. 2020 Jun;20(6):1668-1678. doi: 10.1111/ajt.15817. Epub 2020 Mar 8.