髋膝关节置换术后长效局部麻醉镇痛的快速健康评估
Rapid Health Evaluation of Analgesia with Long-Acting Local Anesthesia After Hip and Knee Arthroplasty.
作者信息
Zhang Xiaoyue, Li Mengting, Lei Luwen
机构信息
Department of Pharmacy, Department of The Sixth Affiliated Hospital, School of Medicine, South China University of Technology, Foshan, People's Republic of China.
出版信息
Integr Pharm Res Pract. 2025 Jun 9;14:99-112. doi: 10.2147/IPRP.S516724. eCollection 2025.
PURPOSE
To evaluate the local anesthetic drugs commonly used after hip arthroplasty and knee arthroplasty, and to provide a reference for clinical drug use and drug selection in medical institutions.
METHODS
Based on the "Quick Guide for Drug Evaluation and Selection in Chinese Medical Institutions (Second Edition)", the included drugs were evaluated from five dimensions of pharmaceutical properties, effectiveness, safety, economy, and other attributes using a 100-point scoring method.
RESULTS
The quantitative scoring results were ranked from high to low as Dishili-Ropivacaine injection (75 points), Naropin-Ropivacaine injection (68.97 points), liposomal bupivacaine (65.06 points), bupivacaine injection (61.05 points), and levobupivacaine injection (60.35 points).
CONCLUSION
The Dishili-Ropivacaine injection of the collectible variety is a strongly recommended variety, which is recommended to be introduced or retained in the drug catalog of medical institutions, and the Naropin-Ropivacaine injection and liposomal bupivacaine can be adjusted according to the actual situation and clinical needs of medical institutions.
目的
评估髋关节置换术和膝关节置换术后常用的局部麻醉药物，为医疗机构临床用药及药物选择提供参考。
方法
依据《中国医疗机构药品评价与遴选快速指南（第二版）》，采用百分制评分法从药学特性、有效性、安全性、经济性及其他属性五个维度对纳入药物进行评价。
结果
定量评分结果由高到低依次为迪施利-罗哌卡因注射液（75分）、耐乐品-罗哌卡因注射液（68.97分）、布比卡因脂质体（65.06分）、布比卡因注射液（61.05分）、左旋布比卡因注射液（60.35分）。
结论
可收集品种迪施利-罗哌卡因注射液为强烈推荐品种，建议医疗机构药品目录引进或保留，耐乐品-罗哌卡因注射液和布比卡因脂质体可根据医疗机构实际情况及临床需求调整。
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