Vinogradova M S, Korostyshevskaia I M
Arkh Patol. 1975;37(6):41-5.
In order to obtain an additional information concerning a possible functional role of the main types of the endocrine cells (EC and ECL) on investigation of aspiration biopsy specimens taken from the middle third of the stomach in patients with ulcerative disease of the duodenum and chronic gastritis was carried out. Changes in morphology, distribution and number of the endocrine cells in pathology of the mucosa and in various acidity of the gastric juice were followed up. On the basis of the data obtained the conclusion is made that serotonin-producing (EC) cells seem to have nothing to do with the regulation of the activity of the fundal glands, whereas the enterochromaffin-like cells (ECL) influence the production of hydrochloric acid by pavement cells.
为了获得有关内分泌细胞(EC细胞和ECL细胞)主要类型可能的功能作用的更多信息,对十二指肠溃疡病和慢性胃炎患者胃中三分之一处的穿刺活检标本进行了研究。观察了黏膜病理状态及胃液不同酸度情况下内分泌细胞的形态、分布和数量变化。根据所获数据得出结论:产生5-羟色胺的(EC)细胞似乎与胃底腺活动的调节无关,而肠嗜铬样细胞(ECL)影响壁细胞盐酸的分泌。