Wu Junjun, Wang Lei, Zhao Pengpeng, Lin Fuxiang, Xu Zhanping
The Eighth Clinical Medical College of Guangzhou University of Chinese Medicine, Foshan, 528099, Guangdong, China.
Zhongshan Hospital of Traditional Chinese Medicine Affiliated to Guangzhou University of Traditional Chinese Medicine, Zhongshan, 614001, Guangdong, China.
Urol Case Rep. 2025 May 28;61:103083. doi: 10.1016/j.eucr.2025.103083. eCollection 2025 Jul.
Primary squamous cell carcinoma (SCC) of the renal parenchyma represents an exceptionally rare malignancy. We present an SCC case demonstrating renal pelvis invasion, histopathologically confirmed following radical nephrectomy. Postoperative adjuvant chemotherapy was initiated, with subsequent development of pulmonary and adrenal metastases at the 10th-month follow-up. After treatment adjustment, the patient is currently 12 months after the operation and is in good general condition. This case illustrates that a definitive diagnosis of primary renal parenchymal SCC remains achievable despite concomitant renal pelvis involvement, emphasizing the importance of comprehensive histopathological evaluation in such rare presentations.
肾实质原发性鳞状细胞癌（SCC）是一种极为罕见的恶性肿瘤。我们报告一例肾实质原发性鳞状细胞癌病例，该病例显示肾盂受侵，根治性肾切除术后经组织病理学证实。术后开始辅助化疗，在第10个月随访时出现肺和肾上腺转移。调整治疗方案后，患者目前术后12个月，一般状况良好。该病例表明，尽管伴有肾盂受累，但原发性肾实质鳞状细胞癌仍可实现明确诊断，强调了在此类罕见病例中进行全面组织病理学评估的重要性。
