Fotovat Amirreza, Gheitasvand Mohsen, Amini Erfan, Ayati Mohsen, Nowroozi Mohammad Reza, Sharifi Laleh
Uro-Oncology Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Department of Pathology, Faculty of Medicine, Lorestan University of Medical Sciences, Khorramabad, Iran.
Urol Case Rep. 2021 Mar 4;37:101627. doi: 10.1016/j.eucr.2021.101627. eCollection 2021 Jul.
Primary squamous cell carcinoma (SCC) of renal parenchyma is very rare and until now only a few cases have been reported. We report a unique SCC case in terms of aggressive nature and metastatic pattern. Renal rubber consistency and pasty keratin secretions were important findings in our patient. The patient underwent radical nephrectomy and lymphadenectomy and received 4 cycles of chemotherapy with cisplatin and gemcitabine. Eight month later, she succumbed the disease after developing ovary metastasis and not responding to chemotherapy. Also, our study showed that SCC may be present in pyelonephritic kidneys without a specific radiologic finding.
肾实质原发性鳞状细胞癌（SCC）非常罕见，迄今为止仅有少数病例报道。我们报告了1例在侵袭性和转移模式方面独特的SCC病例。肾质地如橡胶及糊状角蛋白分泌物是我们这位患者的重要发现。患者接受了根治性肾切除术和淋巴结清扫术，并接受了4个周期的顺铂和吉西他滨化疗。8个月后，她在出现卵巢转移且化疗无效后死于该疾病。此外，我们的研究表明，肾盂肾炎性肾脏中可能存在SCC，且无特定的影像学表现。
