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埃塞俄比亚五岁以下儿童营养不良的建模与绘图:贝叶斯空间分析

Modeling and mapping under-nutrition among under-five children in Ethiopia: a Bayesian spatial analysis.

作者信息

Habtewold Fekade Getabil, Arero Butte Gotu

机构信息

Department of Mathematics, Kotebe University of Education, Addis Ababa, Ethiopia.

Department of Statistics, Addis Ababa University, Addis Ababa, Ethiopia.

出版信息

Front Public Health. 2025 May 30;13:1553908. doi: 10.3389/fpubh.2025.1553908. eCollection 2025.

Abstract

Malnutrition remains a critical global challenge, characterized by an imbalance between nutrient requirements and consumption. Under-nutrition, a specific form of malnutrition, results from inadequate intake of essential nutrients and has severe implications for young children, especially in developing countries. This study aims to model under-nutrition cases among children under five in Ethiopia, utilizing Bayesian spatial models to identify effective interventions. Four models were considered: Generalized Linear Model (GLM), Generalized Linear Mixed Models (GLMM), Intrinsic Conditional Autoregressive (ICAR), and Conditional Autoregressive Besag-York-Mollié (CAR BYM) with negative binomial distribution. The rationale for employing multiple models stems from the need to compare performance and accuracy in capturing spatial heterogeneity. The data were obtained from the Ethiopian Demographic and Health Survey 2019. The parameter estimation was carried out using Bayesian Markov Chain Monte Carlo (MCMC) through the brms package in R, which interfaces with Stan for efficient sampling. The models were evaluated based on the Watanabe Akaike Information Criterion (WAIC) and Leave-One-Out (LOO) cross-validation, with CAR BYM emerging as the best-fitting model. Spatial modeling revealed that maternal age, breastfeeding practices, access to clean water and sanitation facilities, cooking practices, maternal education, and wealth status significantly influence the number of under-nutrition cases among children under five in Ethiopia. Specifically, lower maternal education, poorer wealth status, and inadequate access to clean water and sanitation were associated with an increased number of under-nutrition cases, while improved breastfeeding practices, rich wealth status and higher maternal education were associated with decreased number of cases. Regional disparities also played a significant role, with the CAR BYM model effectively identifying high-risk regions such as Somali, Afar, and parts of Oromia, identified as areas requiring targeted intervention.

摘要

营养不良仍然是一项严峻的全球挑战,其特征是营养需求与摄入量之间的失衡。营养不足是营养不良的一种具体形式,是由于必需营养素摄入不足所致,对幼儿,尤其是发展中国家的幼儿有严重影响。本研究旨在对埃塞俄比亚五岁以下儿童的营养不足情况进行建模,利用贝叶斯空间模型来确定有效的干预措施。考虑了四种模型:广义线性模型(GLM)、广义线性混合模型(GLMM)、内在条件自回归(ICAR)以及具有负二项分布的条件自回归贝萨克 - 约克 - 莫利埃(CAR BYM)模型。采用多种模型的基本原理源于需要比较在捕捉空间异质性方面的性能和准确性。数据取自2019年埃塞俄比亚人口与健康调查。参数估计通过R语言中的brms包使用贝叶斯马尔可夫链蒙特卡罗(MCMC)方法进行,该包与Stan接口以实现高效抽样。基于渡边赤池信息准则(WAIC)和留一法(LOO)交叉验证对模型进行评估,结果显示CAR BYM模型是拟合效果最佳的模型。空间建模表明,母亲年龄、母乳喂养习惯、获得清洁水和卫生设施的情况、烹饪习惯、母亲教育程度和财富状况对埃塞俄比亚五岁以下儿童营养不足病例数有显著影响。具体而言,母亲教育程度较低、财富状况较差以及获得清洁水和卫生设施的机会不足与营养不足病例数增加有关,而改善母乳喂养习惯、富裕的财富状况和较高的母亲教育程度与病例数减少有关。地区差异也起到了重要作用,CAR BYM模型有效识别出了诸如索马里、阿法尔以及奥罗米亚部分地区等高风险地区,这些地区被确定为需要有针对性干预的区域。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/87a7/12162586/1999dc4dce4a/fpubh-13-1553908-g001.jpg

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