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孕晚期白蛋白水平与产后肛提肌破裂风险之间的相关性。

Correlation between albumin levels during the third trimester and the risk of postpartum levator ani muscle rupture.

作者信息

Cai Yueyun, Cai Yuting, Hu Yuanling, Lu Shengkai, Lin Yueqing

机构信息

Department of Obstetrical, Zhangzhou Affiliated Hospital of Fujian medical University, Fujian, 363000, P.R. China.

Department of Obstetrical, Zhangzhou Affiliated Hospital of Fujian medical University, 193 Shuixian Street, Longwen District, Zhangzhou, Fujian, 363000, P.R. China.

出版信息

Open Med (Wars). 2025 Jun 9;20(1):20251209. doi: 10.1515/med-2025-1209. eCollection 2025.

Abstract

OBJECTIVE

To investigate the correlation between albumin levels during the third trimester and the risk of postpartum levator ani muscle rupture.

METHODS

A retrospective analysis of 410 parturients undergoing vaginal delivery at Zhangzhou Hospital Affiliated to Fujian Medical University was conducted. Parturients were classified into low-albumin (<35 g/L) and normal-albumin (≥35 g/L) groups based on their albumin levels during the third trimester. Data on levator ani muscle rupture and various clinical parameters were collected and analyzed using multivariate binary logistic regression.

RESULTS

The low-albumin group comprised 38.29% of participants and had a significantly higher incidence of levator ani muscle rupture (53.50%) compared to the normal-albumin group (33.20%; < 0.05). Albumin levels strongly correlated with rupture risk ( = 0.193, < 0.001). Multivariate analysis showed low albumin levels were an independent risk factor (OR = 2.286, 95% CI: 1.259-4.152). Other independent risk factors included forceps-assisted delivery, BMI ≥ 24 kg/m², age ≥ 35 years, and second stage of labor duration ≥ 120 min (all < 0.05).

CONCLUSION

Decreased albumin levels are an independent risk factor for postpartum levator ani muscle rupture, suggesting a potential role in increasing the risk of muscle injury.

摘要

目的

探讨孕晚期白蛋白水平与产后肛提肌破裂风险之间的相关性。

方法

对福建医科大学附属漳州医院410例经阴道分娩的产妇进行回顾性分析。根据产妇孕晚期的白蛋白水平,将其分为低白蛋白组(<35 g/L)和正常白蛋白组(≥35 g/L)。收集肛提肌破裂及各种临床参数的数据,并采用多因素二元逻辑回归进行分析。

结果

低白蛋白组占参与者的38.29%,与正常白蛋白组(33.20%;<0.05)相比,肛提肌破裂发生率显著更高(53.50%)。白蛋白水平与破裂风险密切相关(=0.193,<0.001)。多因素分析显示,低白蛋白水平是一个独立的危险因素(OR = 2.286,95%CI:1.259 - 4.152)。其他独立危险因素包括产钳助产、BMI≥24 kg/m²、年龄≥35岁以及第二产程时长≥120分钟(均<0.05)。

结论

白蛋白水平降低是产后肛提肌破裂的独立危险因素,提示其在增加肌肉损伤风险方面可能发挥作用。

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