Dadzie Aaron I, Somers Sydney, Dunklebarger Mitchell, Ormiston Laurel, Yamashiro Duane, Gociman Barbu
From the Division of Plastic and Reconstructive Surgery, Department of Surgery, University of Utah School of Medicine, Salt Lake City, UT.
Plast Reconstr Surg Glob Open. 2025 Jun 13;13(6):e6891. doi: 10.1097/GOX.0000000000006891. eCollection 2025 Jun.
Mandibular distraction osteogenesis is a major modality in treating micrognathia associated with severe class II malocclusion. Shortcomings associated with mandibular distraction are often secondary to lack of adequate bone at the level of the osteotomies, either from insufficient original bone stock or paucity of bone secondary to previous surgical procedures. To address the challenge of limited bone availability at the distraction site, our institution has implemented a stepwise protocol in the patients with severe class II malocclusion and insufficient bone stock at the level of the planned osteotomy. Extraction of the mandibular third molar(s), followed by grafting of the resulting defect is performed initially. Either autologous bone graft or the combination graft material consisting of a mixture of demineralized bone matrix, bone morphogenic protein, and freeze-dried bone chips is used. Computed tomography is performed 9 months later to assess the bone stock at the level of the graft site. This technique is presented here with 100% graft take in all 9 grafted sites (6 patients). This technique appears to offer an effective way to prepare the mandible for optimization of subsequent mandibular distraction in patients with severely micrognathic mandibles and insufficient bone stock posterior to the third molar. Of note, both autologous bone and the mixture of demineralized bone matrix, bone morphogenic protein, and freeze-dried bone chips seem equally efficacious.
下颌骨牵张成骨术是治疗与严重II类错牙合相关的小下颌畸形的主要方法。下颌骨牵张相关的缺点通常继发于截骨水平处骨量不足,这要么是由于原始骨量不足,要么是由于先前手术导致的骨量缺乏。为应对牵张部位骨量有限的挑战,我们机构对患有严重II类错牙合且计划截骨水平处骨量不足的患者实施了一种分步方案。首先拔除下颌第三磨牙,然后对 resulting defect 进行植骨。使用自体骨移植或由脱矿骨基质、骨形态发生蛋白和冻干骨碎片混合而成的复合移植材料。9个月后进行计算机断层扫描以评估植骨部位的骨量。本文介绍了该技术,9个植骨部位(6例患者)的植骨全部成功。该技术似乎为严重小下颌且第三磨牙后方骨量不足的患者准备下颌骨以优化后续下颌骨牵张提供了一种有效方法。值得注意的是,自体骨以及脱矿骨基质、骨形态发生蛋白和冻干骨碎片的混合物似乎同样有效。