Nemoto T, Ohara-Nemoto Y, Ota M
Biochem Biophys Res Commun. 1985 Sep 30;131(3):1139-45. doi: 10.1016/0006-291x(85)90209-8.
Nontransformed glucocorticoid receptor stabilized with sodium molybdate exists as the heterogeneous forms which have slight differences in net charges and sedimentation coefficients. These differences could be detected by sequential analyses with DEAE-Sephacel chromatography and glycerol gradient centrifugation. The heterogeneity in the nontransformed receptor appears to be caused by the association of an acidic component(s) with the transformed receptor.
用钼酸钠稳定的未转化糖皮质激素受体以净电荷和沉降系数略有差异的异质形式存在。这些差异可以通过DEAE-琼脂糖凝胶色谱和甘油梯度离心的顺序分析来检测。未转化受体中的异质性似乎是由一种酸性成分与转化受体的结合引起的。
