湿性年龄相关性黄斑变性患者中文版财务毒性量表的验证
Validation of the Chinese version of the financial toxicity scale in patients with wet age-related macular degeneration.
作者信息
Chen Xiuli, Bian Hong, Wu Zhifeng
机构信息
Jiangnan University, Wuxi No 2 People's Hospital, No.68,Zhongshan Road, Wuxi, China.
出版信息
J Patient Rep Outcomes. 2025 Jun 16;9(1):69. doi: 10.1186/s41687-025-00909-x.
OBJECTIVE
to confirm the validity of the Comprehensive Score for Financial Toxicity (COST) Scale in Chinese patients with wet age-related macular degeneration.
METHODS
A tertiary hospital in Wuxi's ophthalmology outpatient clinic treated 217 patients with wet age-related macular degeneration (wAMD) were chosen using the convenience sample approach for a questionnaire survey between October 2023 and February 2024. The Chinese version of the COST and general patient information were included in the survey. Critical ratio analysis and correlation analysis were used to examine the items on the scale. The structural validity of the scale was evaluated using factor analysis, the reliability of the scale was evaluated using Cronbach's α coefficient and retest reliability, and the content validity of the scale was evaluated using the Content Validity Index (CVI).
RESULTS
The item analysis results demonstrated that high and low subgroups could be identified using The COST scale's Chinese translation (P < 0.01).; A linear positive correlation was observed between the scores of each item and the scale's overall scores (r values of 0.243 ~ 0.878, P < 0.01), and the scores of factor 1, factor 2, and factor 3 showed a linear positive correlation with the total scores of the scale (accordingly, r values were 0.974, 0.505, and 0.300; P < 0.01). and the scores of each item were linearly and positively correlated with the scores of the common factors to which they belonged (r values of 0.642 to 1.000, P < 0.01). Content validity showed that the I-CVI of each item was 0.857 ~ 1.00, and the S-CVI was 0.974. Three metrics in all, with a cumulative variance contribution rate of 67.739%, were obtained through exploratory factor analysis. Each item's loading on the corresponding dimensions varied from 0.638 to 0.954. The Cronbach's α coefficient for the entire scale was 0.876(95% CI: 0.85-0.899). The reliability of the retest was 0.970 (95% CI: 0.936-0.990).
CONCLUSION
The Chinese version of the COST scale shows potential applicability pending further validation.
目的
验证财务毒性综合评分（COST）量表在中国湿性年龄相关性黄斑变性患者中的有效性。
方法
采用便利抽样法，选取2023年10月至2024年2月在无锡某三级医院眼科门诊就诊的217例湿性年龄相关性黄斑变性（wAMD）患者进行问卷调查。调查问卷包括COST量表中文版和患者一般信息。采用临界比率分析和相关性分析对量表项目进行检验。采用因子分析评估量表的结构效度，采用Cronbach's α系数和重测信度评估量表的信度，采用内容效度指数（CVI）评估量表的内容效度。
结果
项目分析结果表明，使用COST量表的中文翻译可以区分高分组和低分组（P < 0.01）；各项目得分与量表总分呈线性正相关（r值为0.243～0.878，P < 0.01），因子1、因子2和因子3的得分与量表总分呈线性正相关（相应地，r值分别为0.974、0.505和0.300；P < 0.01），各项目得分与其所属共同因子得分呈线性正相关（r值为0.642至1.000，P < 0.01）。内容效度显示，各项目的I-CVI为0.857～1.00，S-CVI为0.974。通过探索性因子分析得到3个公因子，累积方差贡献率为67.739%。各项目在相应维度上的载荷为0.638至0.954。整个量表的Cronbach's α系数为0.876（95%CI：0.85 - 0.899）。重测信度为0.970（95%CI：0.936 - 0.990）。
结论
COST量表中文版显示出潜在的适用性，有待进一步验证。
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