基于全球疾病负担数据的中国年龄相关性黄斑变性的流行病学负担分析。
Analysis of the epidemiological burden of age-related macular degeneration in China based on the data of global burden of disease.
机构信息
Health Management Center, Third Xiangya Hospital, Central South University, Changsha 410013.
Department of Ophthalmology, Third Xiangya Hospital, Central South University, Changsha 410013.
出版信息
Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2023 Jan 28;48(1):106-113. doi: 10.11817/j.issn.1672-7347.2023.220368.
OBJECTIVES
Age-related macular degeneration (AMD) is one of the 3 major eye diseases recognized by WHO to prevent blindness, and which is the main cause of irreversible visual impairment in the elderly. This study aims to analyze the disease epidemiological burden, and provide a theoretical foundation for the prevention and control of AMD in China based on the data in global burden of disease (GBD) 2019.
METHODS
The prevalent cases/prevalence, disability-adjusted life year (DALYs)/DALY rate of AMD and socio-demographic index (SDI) for global and China were searched from the GBD 2019 database to analyze the epidemiological trend, age-period-gender trend of AMD in China from 1990 to 2019, and to evaluate the relations between the prevalence and SDI.
RESULTS
In 2019, the prevalence of AMD in China was at a high level in the world, and the number of prevalent cases were 1.93 times of that in 1990. The prevalence and DALY rates continued to rise. The age trend of AMD in China was high at the middle of the age stages and low at the two ends, and which was higher in the female than in the male. With the increase of SDI, the prevalence of AMD was increased linearly.
CONCLUSIONS
The disease burden of AMD in China is increased significantly and is positively correlated with the social development from 1990 to 2019. It is of great significance to study the relationship between epidemilolgical data of AMD and social development level for diagnosis treatment and policy of AMD.
目的
年龄相关性黄斑变性（AMD）是世界卫生组织（WHO）认定的三大致盲眼病之一，也是老年人不可逆视力损害的主要原因。本研究旨在基于 2019 年全球疾病负担（GBD）数据，分析疾病的流行病学负担，为中国 AMD 的预防和控制提供理论依据。
方法
从 GBD 2019 数据库中搜索全球和中国 AMD 的现患病例/流行率、伤残调整生命年（DALY）/DALY 率和社会人口指数（SDI），分析中国 AMD 的流行病学趋势、1990 年至 2019 年的年龄、时期和性别趋势，并评估流行率与 SDI 之间的关系。
结果
2019 年，中国 AMD 的流行率在全球处于较高水平，现患病例数是 1990 年的 1.93 倍。流行率和 DALY 率持续上升。中国 AMD 的年龄趋势是中龄段较高，两端较低，女性高于男性。随着 SDI 的增加，AMD 的流行率呈线性增加。
结论
1990 年至 2019 年，中国 AMD 的疾病负担显著增加，与社会发展呈正相关。研究 AMD 的流行病学数据与社会发展水平之间的关系，对 AMD 的诊断治疗和政策制定具有重要意义。
Zotero 插件