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青少年和年轻成年人使用磁控髓内延长钉的临床和影像学结果:一项回顾性队列研究

Clinical and radiological outcomes of magnetically controlled intramedullary lengthening nails in adolescents and young adults: a retrospective cohort study.

作者信息

Talmaç Mehmet Ali, Civan Melih, Mendes Ergün

机构信息

Department of Orthopaedics and Traumatology, Başakşehir Çam ve Sakura City Hospital, Istanbul, Turkey.

Department of Anesthesiology and Reanimation, Faculty of Medicine Hospital, Koç University, Istanbul, Türkiye.

出版信息

J Orthop Surg Res. 2025 Jun 16;20(1):592. doi: 10.1186/s13018-025-06009-2.

DOI:10.1186/s13018-025-06009-2
PMID:40524232
Abstract

BACKGROUND

Magnetically controlled intramedullary lengthening nails offer a fully internal approach to limb lengthening, avoiding complications associated with external fixators such as pin site infections and soft tissue transfixation. While their use in adults is well-documented, evidence regarding their safety and efficacy in adolescents and young adults remains limited.

METHODS

This retrospective cohort study evaluated the clinical and radiological outcomes of 24 limb lengthening procedures performed in 18 adolescent and young adult patients between 2022 and 2024 using PRECICE intramedullary lengthening nails. Patients aged ≤ 18 years with a minimum of 9 months follow-up were included. Lengthening parameters, regenerate morphology, complication rates, and inter-group comparisons were analyzed.

RESULTS

A total of 24 long bone segments (femur, tibia, and humerus) underwent lengthening in 19 sessions. The mean follow-up period was 18.8 months. The average length gained was 45.7 ± 10.5 mm, with a distraction rate of 1.0 ± 0.1 mm/day. Complications requiring return to the operating room occurred in 16% of cases, while 5.3% had minor unresolved issues at treatment completion. Radiographic analysis revealed favorable regenerate morphology, and no case showed regenerate insufficiency. Statistical comparison revealed a significantly higher distraction rate in femoral versus tibial lengthenings (p = 0.036).

CONCLUSIONS

Fully internal limb lengthening using magnetically controlled nails is a safe and effective option for adolescents and young adults, with a low rate of complications and high-quality regenerate formation. These findings support broader adoption of internal lengthening in younger patients, particularly in centers with trained teams and appropriate patient selection.

摘要

背景

磁控髓内延长钉为肢体延长提供了一种完全内置的方法,避免了与外固定器相关的并发症,如针道感染和软组织贯穿固定。虽然其在成人中的应用已有充分记录,但关于其在青少年和年轻成人中的安全性和有效性的证据仍然有限。

方法

这项回顾性队列研究评估了2022年至2024年间18例青少年和年轻成人患者使用PRECICE髓内延长钉进行的24例肢体延长手术的临床和放射学结果。纳入年龄≤18岁且至少随访9个月的患者。分析了延长参数、再生形态、并发症发生率和组间比较。

结果

共19次手术对24个长骨段(股骨、胫骨和肱骨)进行了延长。平均随访期为18.8个月。平均延长长度为45.7±10.5毫米,牵张速率为1.0±0.1毫米/天。16%的病例出现需要返回手术室的并发症,5.3%的患者在治疗结束时存在未解决的小问题。影像学分析显示再生形态良好,无一例出现再生不足。统计比较显示,股骨延长与胫骨延长的牵张速率显著更高(p = 0.036)。

结论

对于青少年和年轻成人,使用磁控钉进行完全内置的肢体延长是一种安全有效的选择,并发症发生率低,再生质量高。这些发现支持在年轻患者中更广泛地采用内置延长,特别是在有训练有素的团队和适当患者选择的中心。

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本文引用的文献

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Cureus. 2025 Jan 10;17(1):e77212. doi: 10.7759/cureus.77212. eCollection 2025 Jan.
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Evaluation of simultaneous bilateral femoral distraction osteogenesis with antegrade intramedullary lengthening nails in achondroplasia with rhizomelic short stature: a retrospective study of 15 patients with a minimum follow-up of 2 years.成骨不全症伴四肢骨干短小的双侧股骨同步撑开延长与顺行髓内钉延长术的疗效评估:15 例患者至少 2 年的回顾性研究。
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已有植入式可编程设备患者的磁驱动髓内肢体延长:病例系列
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J Pediatr Orthop. 2022 Feb 1;42(2):e192-e200. doi: 10.1097/BPO.0000000000002016.
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Limb lengthening with PRECICE magnetic nail in pediatric patients: A systematic review.小儿患者使用PRECICE磁性髓内钉进行肢体延长:一项系统评价
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Femoral lengthening using the Precice intramedullary limb-lengthening system: outcome comparison following antegrade and retrograde nails.采用 Precice 髓内肢体延长系统进行股骨延长:顺行和逆行钉术后结果比较。
Bone Joint J. 2019 Sep;101-B(9):1168-1176. doi: 10.1302/0301-620X.101B9.BJJ-2018-1271.R1.
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[Application of motorized intramedullary lengthening nails in skeletally immature patients : Indications and limitations].[动力型髓内延长钉在骨骼未成熟患者中的应用:适应证与局限性]
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