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Four Cases of Prurigo Nodularis Requiring Nemolizumab due to Persistent Pruritus or Lesions after Dupilumab Treatment.

作者信息

Mima Yoshihito, Yamamoto Masako, Iozumi Ken

机构信息

Department of Dermatology, Tokyo Metropolitan Police Hospital, Tokyo, Japan.

出版信息

Acta Derm Venereol. 2025 Jun 16;105:adv43419. doi: 10.2340/actadv.v105.43419.

Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ebf5/12186433/5466cca2eeda/ActaDV-105-43419-g001.jpg

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本文引用的文献

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Pathophysiology of Prurigo Nodularis: Neuroimmune Dysregulation and the Role of Type 2 Inflammation.
J Invest Dermatol. 2025 Feb;145(2):249-256. doi: 10.1016/j.jid.2024.06.1276. Epub 2024 Aug 30.
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6
Phase 3 Trial of Nemolizumab in Patients with Prurigo Nodularis.
N Engl J Med. 2023 Oct 26;389(17):1579-1589. doi: 10.1056/NEJMoa2301333.
7
Dupilumab as a novel treatment option for prurigo nodularis.
J Allergy Clin Immunol. 2023 Oct;152(4):870-872. doi: 10.1016/j.jaci.2023.08.011. Epub 2023 Aug 23.
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Dupilumab in patients with prurigo nodularis: two randomized, double-blind, placebo-controlled phase 3 trials.
Nat Med. 2023 May;29(5):1180-1190. doi: 10.1038/s41591-023-02320-9. Epub 2023 May 4.
9
Nemolizumab efficacy in prurigo nodularis: onset of action on itch and sleep disturbances.
J Eur Acad Dermatol Venereol. 2022 Oct;36(10):1820-1825. doi: 10.1111/jdv.18377. Epub 2022 Jul 4.
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Prurigo Nodularis: Review and Emerging Treatments.
Skin Therapy Lett. 2021 May;26(3):5-8.

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