Wang Minfang, Chen Wanjun, He Ying, Xu Ji, Zheng Shasha, Wu Meng
Department of Ultrasound, The Affiliated People's Hospital of Ningbo University, Ningbo, Zhejiang, People's Republic of China.
Int J Womens Health. 2025 Jun 11;17:1739-1744. doi: 10.2147/IJWH.S517310. eCollection 2025.
While histopathology remains the diagnostic gold standard for urothelial carcinoma, this case highlights the emerging role of advanced ultrasonographic techniques in characterizing urethral malignancies. We present a 51-year-old female with a one-month history of refractory lower urinary tract symptoms (urinary frequency, urgency, dysuria, and nocturia) unresponsive to conventional anti-inflammatory therapy. Multimodal ultrasonographic evaluation, incorporating conventional sonography, transrectal ultrasound, elastography, and contrast-enhanced ultrasonography (CEUS), revealed a complex proximal urethral mass with malignant features. Subsequent cystoscopic and histopathological examinations confirmed the diagnosis of primary urethral adenocarcinoma. This case underscores the diagnostic value of comprehensive ultrasound protocols in evaluating female urethral neoplasms.
虽然组织病理学仍然是尿路上皮癌的诊断金标准，但该病例凸显了先进超声技术在尿道恶性肿瘤特征描述方面日益重要的作用。我们报告一名51岁女性，有1个月难治性下尿路症状（尿频、尿急、尿痛和夜尿）病史，对传统抗炎治疗无反应。多模态超声评估，包括传统超声、经直肠超声、弹性成像和对比增强超声（CEUS），发现近端尿道有一个具有恶性特征的复杂肿块。随后的膀胱镜检查和组织病理学检查确诊为原发性尿道腺癌。该病例强调了综合超声方案在评估女性尿道肿瘤中的诊断价值。
