Khristianovich D S, Knubovets T L, Sibel'dina L A, Dronova L M
Biofizika. 1985 Sep-Oct;30(5):905-10.
The work deals with the investigation of possible use of 31P-NMR for revealing metabolism changes in the mouse liver during the development of leukemia. This method was shown to permit observation of the extreme pattern of relative concentrations of sugar phosphate and bioorganic phosphate in the latent period. This observed increase in the metabolic activity of hepatocytes correlates with biophysical shifts found by other methods.
这项工作致力于研究31P-NMR在揭示白血病发展过程中小鼠肝脏代谢变化方面的潜在用途。结果表明，该方法能够在潜伏期观察到磷酸糖和生物有机磷酸盐相对浓度的极端模式。观察到的肝细胞代谢活性增加与其他方法发现的生物物理变化相关。
