二乙酰吗啡（海洛因）在全血及血液各组分中的结合特性。
Binding features of diacetylmorphine (heroin) in whole blood and in blood fractions.
作者信息
Barni Comparini I, Gaggelli E, Marchettini N, Valensin G
出版信息
Biophys J. 1985 Aug;48(2):247-51. doi: 10.1016/S0006-3495(85)83778-4.
Abstract
Binding features of heroin in whole blood and in blood fractions were delineated by measuring the selective spin-lattice relaxation rates of heroin protons in physiologic conditions. Interaction with some receptor located in the whole human blood or in the human plasma was detected and the apparent binding constant calculated (K = 39 mol-1 dm3). Inferences about molecular dynamics of the bound heroin could be also gained.
摘要
通过测量生理条件下 heroin 质子的选择性自旋晶格弛豫率，描绘了 heroin 在全血和血液组分中的结合特征。检测到与位于全血或人血浆中的某些受体的相互作用，并计算出表观结合常数（K = 39 mol-1 dm3）。还可以获得关于结合 heroin 的分子动力学的推断。
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