Shimkevich L L, Tepliakov V G
Biull Eksp Biol Med. 1985 Oct;100(10):504-6.
Experimental staphylococcal sepsis has been examined in the model suggested by the authors. Staphylococcus aureus culture in a 10% CaCl2 solution was injected intramuscularly to 230 adult albino rats. Fundamental signs of sepsis have been revealed: increased mortality (up to 28% in rats weighing 120-140 g) from day 1 to day 45 after infection, development of local infectious foci, bacteremia, septicemia and septicopyemia. The authors describe severe dystrophic changes in septic emboli and bacterial colonies in different organs.
在作者提出的模型中对实验性葡萄球菌败血症进行了研究。将金黄色葡萄球菌培养物置于10%氯化钙溶液中,给230只成年白化大鼠进行肌肉注射。已揭示败血症的基本体征:感染后第1天至第45天死亡率增加(体重120 - 140克的大鼠中死亡率高达28%),出现局部感染灶、菌血症、败血症和脓毒败血症。作者描述了不同器官中脓毒性栓子和细菌菌落的严重营养不良性变化。