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具有侵袭性特征的炎性含牙囊肿的罕见表现:一例病例报告及治疗考量

Unusual presentation of an inflamed dentigerous cyst with aggressive features: A case report with management considerations.

作者信息

Ali Mhammad, Abbas Ali, Alshaer Bisan, Ahmad Karam, Khalil Abdul-Karim

机构信息

Al-Andalus University for Medical Science, Faculty of Dentistry, Syria.

Al-Andalus University for Medical Science, Faculty of Dentistry, Syria.

出版信息

Int J Surg Case Rep. 2025 Aug;133:111516. doi: 10.1016/j.ijscr.2025.111516. Epub 2025 Jun 14.

Abstract

INTRODUCTION

Dentigerous cysts are the second most common odontogenic cysts, typically asymptomatic and discovered incidentally on radiographs surrounding the crown of impacted teeth. They usually present as well-defined unilocular radiolucencies and exhibit non-inflammatory histological characteristics. In rare instances, they may undergo secondary infection or exhibit aggressive behaviour, posing diagnostic and therapeutic challenges.

PRESENTATION OF CASE

A 64-year-old male patient presented with a progressive mandibular expansion and associated pain as a chief complaint. The oral examination revealed a swelling in the anterior portion of mandible with buccal plate expansion. The radiographic and histopathologic features were consistent with the diagnosis of dentigerous cyst. Consequently, the lesion was surgically removed, and no clinical or radiological recurrence was detected during 12 months post-operative follow-up.

DISCUSSION

While previous reports of dentigerous cysts typically describe a benign course with well-defined radiolucent borders, this case presents an aggressive variant with inflammatory changes. Furthermore, while dentigerous cysts are commonly associated with impacted teeth and remain asymptomatic, our case suggests a potential association between lesion size, patient age, and chronic inflammatory response as possible contributors to its aggressive behaviour.

CONCLUSIONS

This case highlights a rare occurrence of aggressive dentigerous cyst with inflammation and cortical perforation. It emphasizes the effectiveness of conservative surgical management and suggests further research on the link between lesion size, age, and unidentified inflammatory factors.

摘要

引言

含牙囊肿是第二常见的牙源性囊肿,通常无症状,在围绕阻生牙冠的X线片上偶然发现。它们通常表现为边界清晰的单房性透射区,具有非炎症性组织学特征。在罕见情况下,它们可能发生继发感染或表现出侵袭性行为,带来诊断和治疗挑战。

病例介绍

一名64岁男性患者以进行性下颌骨膨隆及相关疼痛为主诉就诊。口腔检查发现下颌前部肿胀,颊侧骨板膨隆。影像学和组织病理学特征与含牙囊肿的诊断相符。因此,对病变进行了手术切除,术后12个月的随访中未发现临床或影像学复发。

讨论

虽然之前关于含牙囊肿的报道通常描述为具有边界清晰的透射边界的良性病程,但本病例呈现出一种伴有炎症改变的侵袭性变体。此外,虽然含牙囊肿通常与阻生牙相关且无症状,但我们的病例表明病变大小、患者年龄和慢性炎症反应之间可能存在关联,可能是其侵袭性行为的促成因素。

结论

本病例突出了一种罕见的伴有炎症和皮质穿孔的侵袭性含牙囊肿。它强调了保守手术治疗的有效性,并建议对病变大小、年龄和不明炎症因素之间的联系进行进一步研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7542/12213304/1df2cec5527d/gr1.jpg

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