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评估移动健康应用程序对老年糖尿病患者的有效性:随机对照试验的荟萃分析。

Evaluating Effectiveness of mHealth Apps for Older Adults With Diabetes: Meta-Analysis of Randomized Controlled Trials.

作者信息

Azevedo Renato Ferreira Leitao, Varzino Michael, Steinman Erika, Rogers Wendy A

机构信息

Institute of Gerontology, College of Public Health, University of Georgia, Athens, GA, United States.

College of Applied Health Sciences, University of Illinois Urbana-Champaign, Champaign, IL, United States.

出版信息

J Med Internet Res. 2025 Jun 17;27:e65855. doi: 10.2196/65855.

Abstract

BACKGROUND

The global population is aging rapidly, with projections indicating a doubling of older adults by 2050. Among the chronic conditions affecting this demographic, diabetes stands out due to its prevalence and impact on health. Mobile health (mHealth) app interventions show promise in improving health outcomes, leveraging the widespread adoption of smartphones among older adults.

OBJECTIVE

This meta-analysis aimed to evaluate the effectiveness of mHealth apps specifically tested for older adults with type 1 or type 2 diabetes. It addresses the gap in existing literature by focusing on this age group, aiming to provide insights into the benefits and challenges of these technologies.

METHODS

A meta-analysis of randomized controlled trials (RCTs) was conducted across major databases using PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analysis) guidelines to examine the effectiveness of mHealth apps for improving older adults' diabetes outcomes. Primary outcomes included changes in glycated hemoglobin (HbA), fasting blood glucose, and medication adherence levels. We retrieved 4247 papers, of which 257 were moved to full review, and 7 were identified following our criteria. Papers were excluded if the study was not an RCT, did not examine the effect of mHealth apps, or was not conducted with older adults. We provide a mixed methods perspective, pairing the effect sizes in the literature with a review of features included in these apps, allowing for a more comprehensive comparison and reference for future RCT interventions with similar technologies designed for older adults.

RESULTS

Overall, our results indicated that mHealth app interventions can be effective for managing blood glucose in older adult populations. The 7 RCTs that met the inclusion criteria involved a total of 490 participants. The meta-analysis revealed a significant reduction in HbA levels (Hedges g -0.40, 95% CI -0.75 to -0.06) among older adults using mHealth apps. Limited data on fasting blood glucose and medication adherence showed positive trends, echoing the main HbA findings.

CONCLUSIONS

mHealth apps demonstrated effectiveness in improving glycemic control among older adults with diabetes, highlighting their potential as tools for health management in this demographic. Our effect sizes were comparable with other meta-analyses conducted across different aging groups, suggesting that diabetes mHealth apps can be as effective for older adults compared to younger cohorts. Some data suggests that the effectiveness of mHealth apps might decrease over trial time. These findings underscore the need for further research to refine these interventions and optimize their impact on older adults' health outcomes. We evaluated each RCT intervention and identified app components that could relate to the app's effectiveness to guide the design of future diabetes management RCTs and mHealth tools for older adults.

TRIAL REGISTRATION

Open Science Framework 10.17605/OSF.IO/AWVCX; https://osf.io/awvcx.

摘要

背景

全球人口正在迅速老龄化,预计到2050年老年人数量将翻倍。在影响这一人群的慢性病中,糖尿病因其患病率和对健康的影响而格外突出。移动健康(mHealth)应用程序干预措施在改善健康结果方面显示出前景,这得益于智能手机在老年人中的广泛使用。

目的

本荟萃分析旨在评估专门针对1型或2型糖尿病老年人进行测试的移动健康应用程序的有效性。通过关注这一年龄组,本研究填补了现有文献中的空白,旨在深入了解这些技术的益处和挑战。

方法

使用PRISMA(系统评价和荟萃分析的首选报告项目)指南,对各大数据库中的随机对照试验(RCT)进行荟萃分析,以检验移动健康应用程序改善老年人糖尿病结局的有效性。主要结局包括糖化血红蛋白(HbA)、空腹血糖和药物依从性水平的变化。我们检索了4247篇论文,其中257篇进入全文评审,根据我们的标准确定了7篇。如果研究不是随机对照试验、未检验移动健康应用程序的效果或未针对老年人进行,则将论文排除。我们提供了一种混合方法的视角,将文献中的效应量与对这些应用程序所包含功能的综述相结合,以便对未来针对老年人设计的类似技术的随机对照试验干预进行更全面的比较和参考。

结果

总体而言,我们的结果表明,移动健康应用程序干预措施对管理老年人群的血糖可能有效。符合纳入标准的7项随机对照试验共涉及490名参与者。荟萃分析显示,使用移动健康应用程序的老年人中,糖化血红蛋白水平显著降低(Hedges g -0.40,95%CI -0.75至-0.06)。关于空腹血糖和药物依从性的有限数据显示出积极趋势,与糖化血红蛋白的主要研究结果相呼应。

结论

移动健康应用程序在改善糖尿病老年人的血糖控制方面显示出有效性,突出了其作为该人群健康管理工具的潜力。我们的效应量与针对不同年龄组进行的其他荟萃分析相当,这表明糖尿病移动健康应用程序对老年人的效果与年轻人群体相当。一些数据表明,移动健康应用程序的有效性可能会随着试验时间的推移而降低。这些发现强调了进一步研究以完善这些干预措施并优化其对老年人健康结局影响的必要性。我们评估了每项随机对照试验干预措施,并确定了可能与应用程序有效性相关的应用程序组件,以指导未来针对老年人的糖尿病管理随机对照试验和移动健康工具的设计。

试验注册

开放科学框架10.17605/OSF.IO/AWVCX;https://osf.io/awvcx。

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