Ferreira Neto José Soares, Oliveira Jefferson Pinto, Pinho Ana Paula Vilhena Beckman, Pereira Washington Luiz Assunção, Dias Ricardo Augusto, Grisi Filho José Henrique Hidebrand, Gonçalves Vitor Salvador Picão, Heinemann Marcos Bryan, Amaku Marcos, Telles Evelise Oliveira, Ferreira Bruno Fontana Soares, Ferreira Fernando
Faculdade de Medicina Veterinária E Zootecnia, Universidade de São Paulo, Avenida Prof. Dr. Orlando Marques de Paiva, 87, CEP 05508-000, São Paulo, SP, Brasil.
WOAH-Collaborating Centre for Economics of Animal Heath in the Americas Region, Avenida Prof. Dr. Orlando Marques de Paiva, 87, CEP 05508-000, São Paulo, SP, Brasil.
Trop Anim Health Prod. 2025 Jun 18;57(6):278. doi: 10.1007/s11250-025-04530-4.
Bovine brucellosis is an endemic zoonosis in Brazil and the target of a national program for its control and eradication. A sectional study was carried out in Pará to define the best strategies for combating the disease. The state was divided into 3 regions; in each, a random sample of farms was drawn; within each property, blood was collected from a pre-established number of animals to characterize the property as brucellosis infected or free. The animals were screened using the Buffered Acidified Antigen test, followed by retesting of positives using the Complement Fixation test. A total of 9170 animals from 976 farms were tested. The prevalence of infected farms and seropositive animals for the state were 25.7% [CI 95%: 22.9-29.0] and 5.6% [CI 95%: 4.1-8.0], with heterogeneities among regions. Within regions, there was no difference between the prevalence of infected farms for dairy, beef, or mixed ones. The introduction of animals was identified as a risk factor for the disease (OR = 1.38 [CI 95%: 1.01-1.89]). To mitigate the risk of exposure of animals and humans to brucellosis, the state should implement an efficient vaccination program with B19 and RB51 vaccines, seeking to reduce the prevalence of infected farms and animals at low cost. Additionally, to reduce the speed at which the disease spreads, educational actions should be implemented so that cattle and buffalo farmers test animals for brucellosis before introducing them onto their farms.
牛布鲁氏菌病是巴西的一种地方性人畜共患病，也是国家控制和根除计划的目标。在帕拉州开展了一项横断面研究，以确定抗击该疾病的最佳策略。该州被划分为3个区域；在每个区域，随机抽取农场样本；在每个农场内，从预先确定数量的动物身上采集血液，以确定该农场是否感染布鲁氏菌病。使用缓冲酸化抗原试验对动物进行筛查，随后对阳性动物使用补体结合试验进行重新检测。共对976个农场的9170只动物进行了检测。该州感染农场和血清阳性动物的患病率分别为25.7%[95%置信区间：22.9-29.0]和5.6%[95%置信区间：4.1-8.0]，各区域之间存在异质性。在各区域内，奶牛场、肉牛场或混合养殖场感染农场的患病率没有差异。动物引进被确定为该疾病的一个风险因素（比值比=1.38[95%置信区间：1.01-1.89]）。为降低动物和人类接触布鲁氏菌病的风险，该州应实施高效的B19和RB51疫苗接种计划，寻求以低成本降低感染农场和动物的患病率。此外，为降低疾病传播速度，应开展教育行动，使牛和水牛养殖户在将动物引入农场前对其进行布鲁氏菌病检测。
