• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

A 型克劳德·伯纳德·霍纳综合征:颈部神经鞘瘤的恶性肿瘤。

A Claud Bernard Horner syndrome: The malignancy of cervical shwanoma.

作者信息

Sbai Achraf Amine, Bouchlarhem Saad, Benfadil Drissia, Lachkar Azeddine, Idrissi Fahd El Ayoubi El

机构信息

Faculty of Medicine and Pharmacy, Mohammed Ist University, Oujda, Morocco.

Department of Otorhinolaryngology, Mohammed VI University Hospital Mohammed I University Oujda Morocco.

出版信息

Radiol Case Rep. 2025 Jun 6;20(9):4221-4225. doi: 10.1016/j.radcr.2025.04.085. eCollection 2025 Sep.

DOI:10.1016/j.radcr.2025.04.085
PMID:40528918
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12173100/
Abstract

Schwannomas are benign tumors that originate exclusively from Schwann cells, which form the myelin sheath of peripheral nerves. Schwannomas most commonly affect the vagus nerve, although other cranial nerves may also be involved. Involvement of the cervical sympathetic nervous system is exceedingly rare. We report the case of 34-year-old man with no significant medical history. Since the age of 8 years, he had presented with a right upper cervical mass neglected by the patient. The patient had presented for 4 months prior to admission with recurrent infections associated with inflammatory swelling of the mass, febrile episodes and, more recently, the appearance of significant dysphagia and odynophagia. Magnetic resonance imaging with gadolinium contrast confirmed the presence of a well-defined, mass along the cervical sympathetic chain suggestive of a schwannoma developed at the expense of the cervical sympathetic chain. Surgical exploration revealed a homogeneous mass measuring 4.5 × 5 cm, displacing the internal jugular vein anteriorly and the vagus nerve medially, close to the carotid vessels. In the immediate postoperative period, the patient developed isolated right-sided Claude Bernard-Horner syndrome and symptomatic management included a 7-day course of antibiotics and analgesics, as well as eye lubricant drops for 14 days. The clinical course was favorable. Early and appropriate management is essential to optimize functional prognosis and improve the patient's quality of life.

摘要

神经鞘瘤是一种仅起源于施万细胞的良性肿瘤,施万细胞形成周围神经的髓鞘。神经鞘瘤最常累及迷走神经,不过其他颅神经也可能受累。颈交感神经系统受累极为罕见。我们报告一例34岁男性患者,其无重大病史。自8岁起,他就出现了右侧上颈部肿块,一直被患者忽视。患者在入院前4个月出现反复感染,伴有肿块炎性肿胀、发热,最近还出现了明显的吞咽困难和吞咽痛。钆对比剂增强磁共振成像证实沿颈交感神经链存在一个边界清晰的肿块,提示神经鞘瘤以颈交感神经链为代价发展而来。手术探查发现一个大小为4.5×5厘米的均质肿块,将颈内静脉向前推移,迷走神经向内侧推移,靠近颈动脉。术后即刻,患者出现孤立性右侧霍纳综合征,对症治疗包括为期7天的抗生素和镇痛药疗程,以及为期14天的眼部润滑滴眼液。临床过程良好。早期且恰当的治疗对于优化功能预后和改善患者生活质量至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3124/12173100/7006df252f88/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3124/12173100/832317b734cb/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3124/12173100/91297bea04d3/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3124/12173100/0a3164e92ba0/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3124/12173100/7006df252f88/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3124/12173100/832317b734cb/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3124/12173100/91297bea04d3/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3124/12173100/0a3164e92ba0/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3124/12173100/7006df252f88/gr4.jpg

相似文献

1
A Claud Bernard Horner syndrome: The malignancy of cervical shwanoma.A 型克劳德·伯纳德·霍纳综合征:颈部神经鞘瘤的恶性肿瘤。
Radiol Case Rep. 2025 Jun 6;20(9):4221-4225. doi: 10.1016/j.radcr.2025.04.085. eCollection 2025 Sep.
2
Aural toilet (ear cleaning) for chronic suppurative otitis media.慢性化脓性中耳炎的耳道清理(耳部清洁)
Cochrane Database Syst Rev. 2025 Jun 9;6(6):CD013057. doi: 10.1002/14651858.CD013057.pub3.
3
Interventions for central serous chorioretinopathy: a network meta-analysis.中心性浆液性脉络膜视网膜病变的干预措施:一项网状Meta分析
Cochrane Database Syst Rev. 2025 Jun 16;6(6):CD011841. doi: 10.1002/14651858.CD011841.pub3.
4
Pelvic floor muscle training with feedback or biofeedback for urinary incontinence in women.针对女性尿失禁的盆底肌训练及反馈或生物反馈训练
Cochrane Database Syst Rev. 2025 Mar 11;3(3):CD009252. doi: 10.1002/14651858.CD009252.pub2.
5
Indirect comparative efficacy and safety of tirzepatide 10 and 15 mg versus semaglutide 2.4 mg for the management of obesity and overweight in patients with type 2 diabetes.替尔泊肽10毫克和15毫克与司美格鲁肽2.4毫克治疗2型糖尿病患者肥胖和超重的间接比较疗效与安全性
Diabetes Obes Metab. 2025 Jun 19. doi: 10.1111/dom.16508.
6
Systemic antibiotics for chronic suppurative otitis media.用于慢性化脓性中耳炎的全身性抗生素
Cochrane Database Syst Rev. 2025 Jun 9;6(6):CD013052. doi: 10.1002/14651858.CD013052.pub3.
7
Adapting Safety Plans for Autistic Adults with Involvement from the Autism Community.在自闭症群体的参与下为成年自闭症患者调整安全计划。
Autism Adulthood. 2025 May 28;7(3):293-302. doi: 10.1089/aut.2023.0124. eCollection 2025 Jun.
8
St Andrews Referral Delay in Skin Cancer (StARDISC): a study of keratinocyte skin cancer time to treatment, growth, invasiveness, British Association of Dermatologists risk factors and excision adequacy.圣安德鲁斯皮肤癌转诊延迟研究(StARDISC):一项关于角质形成细胞皮肤癌治疗时间、生长、侵袭性、英国皮肤科医师协会危险因素及切除充分性的研究。
Br J Dermatol. 2025 Jun 20;193(1):157-166. doi: 10.1093/bjd/ljaf097.
9
Progestogen for preventing miscarriage in women with recurrent miscarriage of unclear etiology.不明病因复发性流产女性预防流产的孕激素治疗
Cochrane Database Syst Rev. 2025 Jun 11;6(6):CD003511. doi: 10.1002/14651858.CD003511.pub6.
10
Prenatal administration of progestogens for preventing spontaneous preterm birth in women with a multiple pregnancy.孕激素产前给药预防多胎妊娠妇女自发性早产。
Cochrane Database Syst Rev. 2019 Nov 20;2019(11):CD012024. doi: 10.1002/14651858.CD012024.pub3.

本文引用的文献

1
Diagnostic and Therapeutic Strategy for Vagal Schwannoma: Case Series and Literature Review.迷走 schwann 瘤的诊断和治疗策略:病例系列和文献复习。
Medicina (Kaunas). 2023 May 24;59(6):1013. doi: 10.3390/medicina59061013.
2
Challenging diagnosis of cervical vagal nerve schwannoma.颈迷走神经鞘瘤的诊断难题
J Surg Case Rep. 2022 Apr 3;2022(4):rjac084. doi: 10.1093/jscr/rjac084. eCollection 2022 Apr.
3
Extracranial non-vestibular head and neck schwannomas: a case series with the review of literature.颅外非前庭头颈部神经鞘瘤:病例系列及文献复习。
Braz J Otorhinolaryngol. 2022 Nov-Dec;88 Suppl 4(Suppl 4):S9-S17. doi: 10.1016/j.bjorl.2021.05.013. Epub 2021 Jun 9.
4
Development of a gene expression-based prognostic signature for IDH wild-type glioblastoma.基于基因表达的 IDH 野生型胶质母细胞瘤预后标志物的开发。
Neuro Oncol. 2020 Dec 18;22(12):1742-1756. doi: 10.1093/neuonc/noaa157.
5
Effects of radiation based on whole-body irradiation in HTLV-1-infected mice.基于全身照射的辐射对 HTLV-1 感染小鼠的影响。
J Radiat Res. 2019 Oct 23;60(5):705-708. doi: 10.1093/jrr/rrz050.
6
Vagal schwannomas of the head and neck: A comprehensive review and a novel approach to preserving vocal cord innervation and function.头颈部迷走神经鞘瘤:全面综述及保留声带神经支配和功能的新方法。
Head Neck. 2019 Jul;41(7):2450-2466. doi: 10.1002/hed.25758. Epub 2019 Apr 7.
7
Sympathetic Plexus Schwannoma of Carotid Canal: 2 Cases with Surgical Technique and Review of Literature.颈动脉管交感神经丛神经鞘瘤:2例手术技术及文献复习
World Neurosurg. 2018 Oct;118:63-68. doi: 10.1016/j.wneu.2018.06.244. Epub 2018 Jul 9.
8
Using quantitative tissue phenotype to assess the margins of surgical samples from a pan-Canadian surgery study.使用定量组织表型评估加拿大泛手术研究中手术样本的边缘。
Head Neck. 2018 Jun;40(6):1263-1270. doi: 10.1002/hed.25106. Epub 2018 Feb 16.
9
Diagnostic, Surgical, and Postoperative Challenges of Neuroendocrine Tumors of the Neck: Clinical Experience and Literature Review.颈部神经内分泌肿瘤的诊断、手术及术后挑战:临床经验与文献综述
Ann Vasc Surg. 2017 Nov;45:92-97. doi: 10.1016/j.avsg.2017.06.128. Epub 2017 Jul 6.
10
Spinal cord involvement in posterior reversible encephalopathy syndrome (PRES).脊髓受累于后部可逆性脑病综合征(PRES)。
J Neuroradiol. 2016 Feb;43(1):56-8. doi: 10.1016/j.neurad.2015.09.004. Epub 2015 Nov 12.