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学术儿童医院与公共卫生部门合作应对大规模儿童社区结核病暴露。

Academic children's hospital partnership with public health to address mass pediatric community tuberculosis exposure.

作者信息

Sato Alice I, Becken Bradford, Chang Arthur J, Delair Shirley F, Eguiguren Lourdes, Green Hines Andrea, Mowrer Clayton, Skar Gwenn L, Zwiener Jennifer, Neemann Kari

机构信息

Children's Nebraska, Omaha, NE, USA.

University of Nebraska Medical Center, Omaha, NE, USA.

出版信息

Antimicrob Steward Healthc Epidemiol. 2025 Jun 12;5(1):e126. doi: 10.1017/ash.2025.10040. eCollection 2025.

Abstract

OBJECTIVE

To illustrate how a partnership between an academic medical center and a public health department successfully responded to a large tuberculosis (TB) exposure at a community daycare center.

SETTING

A multidisciplinary team rapidly established a dedicated TB Exposure Clinic to evaluate and screen exposed children requiring window prophylaxis.

PATIENTS

The exposure affected 592 individuals, including 359 children under five-those at highest risk for severe disease.

INTERVENTIONS

Given the vulnerability of young children to TB infection, timely evaluation and initiation of window prophylaxis were prioritized.

RESULTS

Over two days, 162 children were assessed for TB window prophylaxis, and 110 additional children underwent TB screening.

CONCLUSIONS

By leveraging clinical expertise, interdisciplinary collaboration, and informatics infrastructure, the TB Exposure Clinic delivered rapid, comprehensive care while minimizing disruption to local healthcare systems. This model underscores the essential role of academic medical centers in supporting public health responses.

摘要

目的

阐述学术医疗中心与公共卫生部门之间的合作关系如何成功应对社区日托中心发生的大规模结核病暴露事件。

背景

一个多学科团队迅速设立了专门的结核病暴露诊所,以评估和筛查需要进行预防性服药的受暴露儿童。

患者

此次暴露事件影响了592人,其中包括359名五岁以下儿童——这些儿童患重症的风险最高。

干预措施

鉴于幼儿易感染结核病,优先进行及时评估并启动预防性服药。

结果

在两天时间里,对162名儿童进行了结核病预防性服药评估,另有110名儿童接受了结核病筛查。

结论

通过利用临床专业知识、跨学科合作和信息学基础设施,结核病暴露诊所提供了快速、全面的护理,同时尽量减少对当地医疗系统的干扰。该模式凸显了学术医疗中心在支持公共卫生应对方面的重要作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/308a/12171945/e046ee84438e/S2732494X25100405_fig1.jpg

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