新型麦角灵类化合物作为5-羟色胺2A受体激动剂用于治疗情绪障碍
Novel Ergolines as 5‑HT2A Agonists for Treating Mood Disorders.
作者信息
Sabnis Ram W
机构信息
Smith, Gambrell & Russell LLP, 1105 W. Peachtree Street NE, Atlanta, Georgia 30309, United States.
出版信息
ACS Med Chem Lett. 2025 May 21;16(6):974-975. doi: 10.1021/acsmedchemlett.5c00288. eCollection 2025 Jun 12.
Abstract
Provided herein are novel ergolines as 5-HT2A agonists, pharmaceutical compositions, use of such compounds in treating mood disorders, and processes for preparing such compounds.
摘要
本文提供了作为5-HT2A激动剂的新型麦角灵、药物组合物、此类化合物在治疗情绪障碍中的用途以及制备此类化合物的方法。
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本文引用的文献
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The evolution of N, N-Dimethyltryptamine: from metabolic pathways to brain connectivity.N，N-二甲基色胺的演变：从代谢途径到脑连接性
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Psychedelic-Induced Neural Plasticity: A Comprehensive Review and a Discussion of Clinical Implications.致幻剂诱导的神经可塑性：全面综述及临床意义探讨
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Exploring DMT: Endogenous role and therapeutic potential.探索二甲基色胺：内源性作用及治疗潜力。
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