Alrajhi Nada Saleh, Albarrati Ali, Aldhahi Monira I, Gwada Rehab F M
Physical Therapy Department, Prince Sultan Military Medical City, Riyadh, Saudi Arabia.
Rehabilitation Health Sciences Department, College of Applied Medical Sciences, King Saud University, Riyadh, Saudi Arabia.
Int J Chron Obstruct Pulmon Dis. 2025 Jun 12;20:1881-1892. doi: 10.2147/COPD.S515494. eCollection 2025.
Chronic obstructive pulmonary disease (COPD) is a progressive respiratory condition marked by airflow limitation and symptoms like chronic cough, breathlessness, and chest tightness. These factors, along with exacerbations and polypharmacy, may predispose COPD patients to urinary incontinence (UI). Unique challenges such as increased intra-abdominal pressure, pelvic floor weakness, and comorbidities may worsen UI and impair health-related quality of life (HRQoL). This study aimed to identify factors associated with UI severity in COPD patients and to examine its impact on HRQoL.
This cross-sectional study included 101 participants diagnosed with COPD who were reported to have UI. Participants completed the following questionnaires: the health status and UI severity were recorded using the COPD Assessment Test (CAT), International Consultation on Incontinence Questionnaire- Urinary Incontinence - short form (ICIQ-UI short form), and Incontinence Impact Questionnaire - short form (IIQ-7).
UI severity was correlated with age, BMI, smoking, comorbidities, medications, chest tightness, and breathlessness. Severe UI predictors included age (OR=1.07), BMI (OR=1.09), and number of medications (OR=5.04), whereas breathlessness predicted moderate (OR=1.72) and severe UI (OR=1.87). Among COPD patients, 82.2% reported a mild impact of UI on HRQoL, and 6.9% reported a severe impact. Notably, among those experiencing moderate-to-severe HRQoL impairment, 63.6% had severe UI.
This study highlights urinary incontinence (UI) as a prevalent and impactful comorbidity in individuals with COPD, significantly affecting their HRQoL. UI severity was associated with clinical factors such as older age, higher body mass index (BMI), greater medication burden, and breathlessness. Notably, greater UI severity corresponded to more substantial impairments in HRQoL, with severe cases reporting greater negative effects on daily functioning. These findings underscore the importance of routine screening for UI in COPD patients and the implementation of targeted continence care strategies to enhance overall quality of life.
慢性阻塞性肺疾病(COPD)是一种进行性呼吸系统疾病,其特征为气流受限以及慢性咳嗽、呼吸急促和胸闷等症状。这些因素,连同病情加重和多种药物治疗,可能使COPD患者易患尿失禁(UI)。诸如腹内压升高、盆底肌无力和合并症等独特挑战可能会使尿失禁恶化并损害健康相关生活质量(HRQoL)。本研究旨在确定与COPD患者尿失禁严重程度相关的因素,并研究其对健康相关生活质量的影响。
这项横断面研究纳入了101名被诊断患有COPD且报告有尿失禁的参与者。参与者完成了以下问卷:使用慢性阻塞性肺疾病评估测试(CAT)、国际尿失禁咨询委员会尿失禁简表(ICIQ-UI简表)和尿失禁影响问卷简表(IIQ-7)记录健康状况和尿失禁严重程度。
尿失禁严重程度与年龄、体重指数、吸烟、合并症、药物治疗、胸闷和呼吸急促相关。严重尿失禁的预测因素包括年龄(OR=1.07)、体重指数(OR=1.09)和药物数量(OR=5.04),而呼吸急促预测中度(OR=1.72)和严重尿失禁(OR=1.87)。在COPD患者中,82.2%报告尿失禁对健康相关生活质量有轻度影响,6.9%报告有严重影响。值得注意的是,在经历中度至重度健康相关生活质量损害的患者中,63.6%有严重尿失禁。
本研究强调尿失禁(UI)是COPD患者中一种普遍且有影响的合并症,显著影响他们的健康相关生活质量。尿失禁严重程度与年龄较大、体重指数(BMI)较高、药物负担较重和呼吸急促等临床因素相关。值得注意的是,尿失禁严重程度越高,健康相关生活质量受损越严重,严重病例报告对日常功能有更大的负面影响。这些发现强调了对COPD患者进行尿失禁常规筛查以及实施有针对性的控尿护理策略以提高总体生活质量的重要性。