Sonmez Gamze, Kalaycı Fatma Naz Cemre, Gocmen Rahsan, Ozsurekcı Yasemin, Cagdas Deniz
Hacettepe University Faculty of Medicine, Ankara, Turkey.
Department of Radiology, Hacettepe University Faculty of Medicine, Ankara, Turkey.
Indian J Radiol Imaging. 2025 Feb 13;35(3):474-480. doi: 10.1055/s-0045-1802329. eCollection 2025 Jul.
The BK virus, an unenveloped double-stranded DNA virus, infects up to 90% of the population, The virus often remains dormant but can reactivate and cause illness under conditions of impaired cellular immunity. It can cause progressive multifocal leukoencephalopathy and has been implicated in a variety of conditions, including encephalitis, nephritis, cystitis, and retinitis. This report explores neurological symptoms linked to the BK virus, focusing on its potential role in spinal cord pathology in patients with combined immunodeficiency by presenting and analyzing two distinct case studies. Although not commonly associated with neurological disorders, there are rarely reports of BK virus involvement in central nervous system diseases.
BK病毒是一种无包膜的双链DNA病毒，感染率高达90%的人群。该病毒通常处于潜伏状态，但在细胞免疫受损的情况下可能重新激活并引发疾病。它可导致进行性多灶性白质脑病，并与多种病症有关，包括脑炎、肾炎、膀胱炎和视网膜炎。本报告通过呈现和分析两个不同的病例研究，探讨与BK病毒相关的神经症状，重点关注其在联合免疫缺陷患者脊髓病变中的潜在作用。虽然BK病毒通常与神经疾病无关，但很少有关于其累及中枢神经系统疾病的报道。
