Niva B, Rajeshkannan Ramiah
Department of Radiology, Amrita Institute of Medical Sciences, Kochi, Kerala, India.
Indian J Radiol Imaging. 2025 Jan 23;35(3):431-441. doi: 10.1055/s-0044-1801762. eCollection 2025 Jul.
The aim of the study was to identify the various spectrum of single ventricle (SV) physiology and to correlate the anatomical variants. All congenital heart disease cases with computed tomography/magnetic resonance imaging during the period from 2008 to 2023 were retrospectively assessed. Among these, we identified those corresponding to the definition of SV ( = 160). In each case, we described the situs, looping, atrioventricular (AV)/ventriculoarterial (VA) connections, and associated anomalies. Descriptive statistics of each parameter were obtained and compared with similar parameters of other published studies. Among the 160 cases, there were 93 males (58.1%) and 67 females (41.9%). The mean age was 8.41 ± 8.84 years. The most common defects were tricuspid atresia (TA) at 28%, double inlet left ventricle (DILV) at 23%, and AV canal defect (AVCD) at 22%. Other conditions include double outlet right ventricle, large ventricular septal defect, dextro-transposition of great arteries, levo-transposition of great arteries, mitral atresia, pulmonary atresia, hypoplastic left heart syndrome, and crisscross heart. There were 123 situs solitus, 28 right isomerism, 4 left isomerism, and 5 situs inversus cases. Among the patients with right isomerism, the most common defect was AVCD (86%). Sixty-five percent of DILV had discordant VA connections, while only 14% showed concordance. Sixty-three percent of TA cases showed VA concordance. Knowing the underlying anatomy in detail helps the physician to anticipate the wide array of problems unique to SV circulation and treat them accordingly. The conditions coming under the SV spectrum can be classified based on AV and VA connections. The incidence of each condition and observed associations were described.
本研究的目的是确定单心室（SV）生理的各种频谱，并将解剖变异进行关联分析。对2008年至2023年期间所有进行了计算机断层扫描/磁共振成像的先天性心脏病病例进行回顾性评估。其中，我们确定了符合SV定义的病例（n = 160）。在每个病例中，我们描述了心脏位置、心环、房室（AV）/心室动脉（VA）连接以及相关异常情况。获得了每个参数的描述性统计数据，并与其他已发表研究的类似参数进行比较。
在这160例病例中，男性93例（58.1%），女性67例（41.9%）。平均年龄为8.41±8.84岁。最常见的缺陷是三尖瓣闭锁（TA），占28%；双入口左心室（DILV），占23%；房室通道缺损（AVCD），占22%。其他情况包括右心室双出口、大型室间隔缺损、大动脉右旋位、大动脉左旋位、二尖瓣闭锁、肺动脉闭锁、左心发育不全综合征和交叉心脏。心脏位置正常者123例，右位异构28例，左位异构4例，心脏位置反位5例。在右位异构患者中，最常见的缺陷是AVCD（86%）。65%的DILV患者VA连接不一致，而只有14%表现为一致。63%的TA病例表现为VA一致。详细了解潜在的解剖结构有助于医生预测SV循环特有的一系列广泛问题，并相应地进行治疗。
SV频谱范围内的情况可根据AV和VA连接进行分类。描述了每种情况的发生率和观察到的关联。
