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单阶段与双阶段双侧全膝关节置换术治疗双侧膝关节骨关节炎疗效的回顾性比较研究

A Retrospective Comparative Study of the Outcomes of Single-Stage Versus Double-Stage Bilateral Total Knee Arthroplasty in the Management of Bilateral Knee Osteoarthritis.

作者信息

Siva Narayana Borusu, S Nagakumar J, Venkataraman Sagar, Thampi Gils

机构信息

Orthopedics, Sri Devaraj Urs Medical College, Sri Devaraj Urs Academy of Higher Education and Research, Kolar, IND.

出版信息

Cureus. 2025 May 17;17(5):e84266. doi: 10.7759/cureus.84266. eCollection 2025 May.

Abstract

Background Osteoarthritis of the knee is a prevalent chronic condition, often necessitating total knee arthroplasty (TKA) when conservative treatments fail. Single-stage and double-stage bilateral TKA procedures are both widely performed, and the optimal approach in terms of perioperative complications and functional outcomes remains debated. This study aims to compare single-stage and double-stage bilateral TKA concerning postoperative recovery, complications, and hospitalization parameters. Methods A retrospective study was conducted at R. L. Jalappa Hospital, Tamaka, Kolar, from August 2023 to July 2024, including 38 patients with Kellgren-Lawrence grade 3 or 4 primary osteoarthritis undergoing bilateral TKA. Patients were divided into two cohorts: Group A (n = 19) underwent single-stage TKA, and Group B (n = 19) underwent double-stage TKA (≤12 months apart). Outcomes assessed included pain (Visual Analogue Scale (VAS)), functional recovery (Oxford Knee Score (OKS), Knee Society Score (KSS)), perioperative complications, transfusion rates, and hospitalization duration. Statistical analyses compared both groups. Results The mean age of participants was comparable (65.74 ± 8.13 years in Group A vs. 65.58 ± 10.01 years in Group B). Both groups exhibited similar preoperative VAS (8.53 ± 1.17 vs. 8.47 ± 0.96), OKS (20.32 ± 3.20 vs. 19.74 ± 3.21), and KSS (50.58 ± 5.09 vs. 50.11 ± 5.5). The single-stage group had a significantly shorter hospital stay (6.21 ± 0.85 days vs. 7.74 ± 1.28 days, p = 0.001). Functional scores at six months showed higher OKS in Group A (50.00 ± 3.23) than Group B (47.95 ± 2.697, p = 0.040), while KSS scores were similar. Perioperative complications included deep vein thrombosis (DVT) in three (7.8%) patients, bleeding in one (2.6%) patient, pulmonary embolism (PE) in one (2.6%) patient, wound healing issues in two (5.3%) patients, and urinary complications in two (5.3%) patients, with no significant difference between groups. Conclusion Single-stage bilateral TKA is associated with shortened hospital stay and improved functional outcomes at six months compared to the double-stage approach, without significant differences in perioperative complications. These findings suggest that single-stage TKA may be a preferable option in carefully selected patients.

摘要

背景

膝关节骨关节炎是一种常见的慢性疾病,保守治疗失败时通常需要进行全膝关节置换术(TKA)。单阶段和双阶段双侧TKA手术均被广泛应用,围手术期并发症和功能结局方面的最佳方法仍存在争议。本研究旨在比较单阶段和双阶段双侧TKA在术后恢复、并发症和住院参数方面的差异。方法:于2023年8月至2024年7月在科拉尔塔马卡的R.L.贾拉帕医院进行了一项回顾性研究,纳入38例患有Kellgren-Lawrence 3级或4级原发性骨关节炎且接受双侧TKA的患者。患者分为两组:A组(n = 19)接受单阶段TKA,B组(n = 19)接受双阶段TKA(间隔≤12个月)。评估的结局包括疼痛(视觉模拟评分法(VAS))、功能恢复(牛津膝关节评分(OKS)、膝关节协会评分(KSS))、围手术期并发症、输血率和住院时间。对两组进行统计学分析。结果:参与者的平均年龄相当(A组为65.74 ± 8.13岁,B组为65.58 ± 10.01岁)。两组术前VAS(8.53 ± 1.17 vs. 8.47 ± 0.96)、OKS(20.32 ± 3.20 vs. 19.74 ± 3.21)和KSS(50.58 ± 5.09 vs. 50.11 ± 5.5)相似。单阶段组的住院时间明显更短(6.21 ± 0.85天 vs. 7.74 ± 1.28天,p = 0.001)。六个月时的功能评分显示,A组的OKS(50.00 ± 3.23)高于B组(47.95 ± 2.697,p = 0.040),而KSS评分相似。围手术期并发症包括3例(7.8%)患者发生深静脉血栓形成(DVT)、1例(2.6%)患者出血、1例(2.6%)患者发生肺栓塞(PE)、2例(5.3%)患者出现伤口愈合问题以及2例(5.3%)患者出现泌尿系统并发症,两组之间无显著差异。结论:与双阶段方法相比,单阶段双侧TKA与缩短住院时间和六个月时改善的功能结局相关,围手术期并发症无显著差异。这些发现表明,在精心挑选的患者中,单阶段TKA可能是更可取的选择。

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