Sumida Hirotaka, Umeda Ikuko, Baba Takayuki
Department of Ophthalmology and Visual Science, Chiba University Graduate School of Medicine, 1-8-1 Inohana, Chuo-ku, Chiba, 260-0856, Japan.
Jpn J Ophthalmol. 2025 Jun 18. doi: 10.1007/s10384-025-01218-y.
To investigate changes in the choroidal area (CA), luminal area (LA), stromal area (SA), choroidal vascularity index (CVI), and choroidal thickness (CT) before and after vitrectomy in eyes with macular hole retinal detachment (MHRD).
Retrospective observational study.
We measured the best-corrected visual acuity (BCVA), intraocular pressure (IOP), CA, LA, SA, CVI, and CT preoperatively and 1, 3, and 6 months postoperatively in 10 eyes with MHRD. CA was measured within a 3-mm-wide area around the fovea in the horizontal and vertical images. LA and SA were quantified using the Niblack method, and CVI was calculated as the ratio of LA to CA. CT was measured at the subfovea and at 1 and 3 mm vertically and horizontally away from the fovea.
BCVA improved significantly at 1 and 3 months postoperatively (P = 0.036 and 0.016). IOP remained stable. CA and LA decreased significantly 6 months postoperatively in both the horizontal (P = 0.002 and 0.014) and vertical sections (P = 0.006 and 0.002). SA remained stable. CVI reduced significantly at 1 month horizontally and at 3 months vertically (both P = 0.027). CT decreased significantly in the subfovea at 3 and 6 months postoperatively (P = 0.027 and 0.020, respectively). Significant reductions were also observed at 1 mm nasal, temporal, and superior regions (P = 0.014, 0.014, and 0.004) and at 2 mm temporal and superior regions 1 month postoperatively (P = 0.020 and 0.014).
Choroidal thinning was observed after vitrectomy in eyes with MHRD, driven by a reduction in the luminal area.
研究黄斑裂孔性视网膜脱离（MHRD）眼玻璃体切除术前、后脉络膜面积（CA）、管腔面积（LA）、基质面积（SA）、脉络膜血管指数（CVI）及脉络膜厚度（CT）的变化。
回顾性观察研究。
我们对10例MHRD患者的患眼术前及术后1、3、6个月测量最佳矫正视力（BCVA）、眼压（IOP）、CA、LA、SA、CVI和CT。在水平和垂直图像中，在黄斑中心凹周围3毫米宽的区域内测量CA。使用Niblack方法对LA和SA进行定量，CVI计算为LA与CA的比值。在黄斑中心凹下以及在垂直和水平方向距黄斑中心凹1毫米和3毫米处测量CT。
术后1个月和3个月时BCVA显著改善（P = 0.036和0.016）。眼压保持稳定。术后6个月时，水平（P = 0.002和0.014）和垂直切面（P = 0.006和0.002）的CA和LA均显著降低。SA保持稳定。水平方向术后1个月和垂直方向术后3个月时CVI显著降低（均为P = 0.027）。术后3个月和6个月时，黄斑中心凹下CT显著降低（分别为P = 0.027和0.020）。术后1个月时，在鼻侧、颞侧和上方1毫米区域（P = 0.014、0.014和0.004）以及颞侧和上方2毫米区域（P = 0.020和0.014）也观察到显著降低。
MHRD眼玻璃体切除术后观察到脉络膜变薄，这是由管腔面积减少所致。
